Impact of phyto-oxylipins in plant defense

doi:10.1016/S1360-1385(02)02290-2

Trends in Plant Science

Volume 7, Issue 7, 1 July 2002, Pages 315-322

https://doi.org/10.1016/S1360-1385(02)02290-2 Get rights and content

Abstract

Phyto-oxylipins are metabolites produced in plants by the oxidative transformation of unsaturated fatty acids via a series of diverging metabolic pathways. Biochemical dissection and genetic approaches have provided compelling evidence that these oxygenated derivatives actively participate in plant defense mechanisms. During the past decade, interest in this field was focused on the biosynthesis of jasmonic acid (one branch of C18 polyunsaturated fatty acid metabolism) and on its relationship to the other plant defense-signaling pathways. However, recently, antisense strategies have revealed that oxylipins other than jasmonates are probably also essential for the resistance of plants to pathogens.

Section snippets

Cytochrome-P450-dependent mono-oxygenases

The oxidation of fatty acids by a single oxygen atom is performed by cytochrome-P450-dependent mono-oxygenases, which catalyze in-chain and ω-hydroxylations of saturated and unsaturated C10 to C18 fatty acids. Recent cloning of fatty-acid hydroxylases from various plant species has revealed that these oxidases differ in their substrate specificity and in their regulation patterns [1]. It is believed that these enzymes play a role in preventing the potentially harmful effects of free-fatty-acid

Regulation of the phyto-oxylipin pathways

Recent analysis has shown that plants contain phyto-oxylipin pools of various sizes, conferring an oxylipin signature [42] on a given organelle, tissue, plant or species. Upon injury, pathogen attack or treatment with elicitors or signal molecules, a sudden and dramatic change in the composition of oxygenated fatty-acid derivatives occurs, often depending on the nature of the stress. For example, salicylic acid triggers an almost exclusive formation of hydroxy-fatty-acid derivatives in barley

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Trends in Plant Science

ReviewImpact of phyto-oxylipins in plant defense

Abstract

Section snippets

Cytochrome-P450-dependent mono-oxygenases

Regulation of the phyto-oxylipin pathways

J. Biol. Chem.

Biochim. Biophys. Acta

J. Biol. Chem.

FEBS Lett.

J. Biol. Chem.

Prog. Lipid Res.

J. Biol. Chem.

Trends Plant Sci.

Trends Plant Sci.

Physiol. Mol. Plant Pathol.

Curr. Opin. Plant Biol.

Curr. Opin. Immunol.

FEBS Lett.

J. Biol. Chem.

J. Biol. Chem.

FEBS Lett.

Functional expression in yeast and characterization of a chlofibrate-inducible plant cytochrome-P450 (CYP94A1) involved in cutin monomers biosynthesis

Biochem. J.

Functional analysis of the LACERATA gene of Arabidopsis provides evidence for different roles of fatty acid ω-hydroxylation in development

Proc. Natl. Acad. Sci. U. S. A.

A dual function α-dioxygenase–peroxidase and NAD+ oxidoreductase active enzyme from germinating pea rationalizing α-oxidation of fatty acids in plants

Plant Physiol.

Abnormal catabolites of unsaturated fatty acids by in vitro reaction of crude enzyme from infected higher plants

Chem. Lett.

PIOX, a new pathogen-induced oxygenase with homology to animal cyclooxygenase

Plant Cell

Molecular interactions between the specialist herbivore Manduca sexta (Lepidoptera, Sphingidae) and its natural host Nicotiana attenuata. I. Large-scale changes in the accumulation of growth- and defense-related plant mRNA

Plant Physiol.

Formation of ketodienoic fatty acids by the pure pea lipoxygenase-1

Eicosanoids

Fatty acid hydroperoxide lyase: a plant cytochrome P450 enzyme involved in wound healing and pest resistance

Chem. Biochem.

An epoxy alcohol synthase pathway in higher plants: biosynthesis of antifungal trihydroxy oxylipins in leaves of potato

Lipids

The incompatible interaction between Phytophtora parasitica var. nicotianae race 0 and tobacco is suppressed in transgenic plants expressing antisense lipoxygenase sequences

Proc. Natl. Acad. Sci. U. S. A.

Mechanism of hypersensitive cell collapse: correlation of increased lipoxygenase activity with membrane damage in leaves of Phaseolus vulgaris (L.) inoculated with an avirulent race of Pseudomonas syringae pv

Physiol. Mol. Plant Pathol.

Fatty acid ketodienes and fatty acid ketotrienes: Michael addition acceptors that accumulate in wounded and diseased Arabidopsis leaves

Plant J.

Review
Impact of phyto-oxylipins in plant defense

A dual function α-dioxygenase–peroxidase and NAD⁺ oxidoreductase active enzyme from germinating pea rationalizing α-oxidation of fatty acids in plants