The proprotein convertases
References (59)
- et al.
Proteolytic processing mechanism in the biosynthesis of neuroendocrine peptides: the subtilisin-like proprotein convertases
Frontiers in Neuroendocrinology
(1995) - et al.
The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions
Biochimie
(1994) - et al.
Processing of wild- type and mutant proinsulin-like growth factor-IA by subtilisin-related proprotein convertases
J Biol Chem
(1997) - et al.
Accurate and efficient cleavage of the human insulin proreceptor by the human proprotein-processing protease furin
J Biol Chem
(1994) - et al.
A second mutant allele of furin in the processing-incompetent cell line, LoVo
J Biol Chem
(1995) - et al.
Endoprotease activities other than furin and PACE4 with a role in processing of HIV-I gp160 glycoproteins in CHO-K1 cells
J Biol Chem
(1997) - et al.
Protein sorting and secretion granule formation in regulated secretory cells
Trends Cell Biol
(1992) - et al.
7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity
J Cell Biol
(1995) - et al.
Structural elements of PC2 required for interaction with its helper protein 7B2
J Biol Chem
(1997) - et al.
Structure-function studies on the biosynthesis and bioactivity of the precursor convertase PC2 and the formation of the PC2/7B2 complex
FEBS Lett
(1995)
Incomplete processing of proinsulin to insulin accompanied by elevation of des-31,32 proinsulin intermediate in islets of mice lacking active PC2
J Biol Chem
(1998)
Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide
J Biol Chem
(1995)
Immunocytochemical localization of prohormone convertases PC1/PC3 and PC2 in rat pancreatic islets
Arch Histol Cytol
(1996)
Measurement of insulin and proinsulin
Diabetes Rev
(1996)
Brief report: impaired processing of prohormones associated with abnormalities of glucose homeostasis and adrenal function
New Engl J Med
(1995)
Effect of carboxypeptidase E deficiency on progastrin processing and gastrin messenger ribonucleic acid expression in mice with the fat mutation
Endocrinology
(1997)
Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpefat mice
Cell
(1997)
Intracellular misrouting and abnormal secretion of adrenocorticotropin and growth hormone in Cpefat mice associated with a carboxypeptidase E mutation
Proc Natl Acad Sci USA
(1997)
Structure for the gene for the testis-specific proprotein convertase 4 and its alternate messenger RNA isoforms
Genomics
(1994)
Proteases and the emerging role of protease inhibitors in prohormone processing
FASEB J
(1994)
Processing of protein precursors by a novel family of subtilisin-related mammalian endoproteases
Bio/Technology
(1993)
A new member of the proprotein convertase gene family (LPC) is located at a chromosome translocation breakpoint in lymphomas
Cancer Res
(1996)
cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases
Proc Natl Acad Sci USA
(1996)
PC8, a new member of the convertase family
Biochem J
(1996)
Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface
EMBO J
(1994)
Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail
EMBO J
(1995)
Two independent targeting signals in the cytoplasmic domain determine trans- Golgi network localization and endosomal trafficking of the proprotein convertase furin
EMBO J
(1995)
Franzusoff A: Isolation of the human PC6 gene encoding the putative host protease for HIV-1 gp160 processing in CD4+ T lymphocytes
Proc Natl Acad Sci USA
(1996)
The effects of clathrin inactivation on localization of kex2 protease are independent of the TGN localization signal in the cytosolic tail of kex2p
Mol Biol Cell
(1996)
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