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From microenteropathy to villous atrophy: what is treatable?

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Cited by (17)

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    2016, Gastroenterology Clinics of North America
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    Subtle structural changes were seen in the duodenal mucosa using confocal endomicroscopy when the small intestines of patients with IBS were directly exposed to certain food antigens.78 This finding suggests that some patients with IBS mount an immunologic response to dietary components leading to a microenteropathy related to primary or acquired food sensitivity such as can be seen PI-IBS.79 Patients report some food constituents as more problematic, such as wheat, fruit, and vegetables, which has led to substantial focus on the role of 2 dietary triggers: gluten and fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs).73,80

  • Refractory celiac disease and EATL patients show severe malnutrition and malabsorption at diagnosis

    2016, Clinical Nutrition
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    In addition, HLA-genotyping was determined, to analyze the incidence of DQ2 and DQ8 haplotypes as a requirement for a conclusive diagnosis. Duodenal biopsy specimens were gathered to define the grade of histological impairment as classified by Marsh [14] (modified by Rostami [15,16]), the gold standard method of diagnosis of CD. CD diagnosis relied on the demonstration of partial or complete villous atrophy (Marsh IIIA-C), and the detection of CD-related antibodies and the presence of CD-related genotypes.

  • Microscopic enteritis: Novel prospect in coeliac disease clinical and immuno-histogenesis. Evolution in diagnostic and treatment strategies

    2009, Digestive and Liver Disease
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    Microscopic enteritis (ME) is the stage of microscopic and sub-microscopic changes (microenteropathy) associated with the symptoms of micronutrient deficiencies [1].

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