Major ArticleBoosted tuberculin skin testing in hemodialysis patients
Section snippets
Methods
A total of 106 patients were recruited from Ondokuz Mayıs University School of Medicine, Hemodialysis Unit, Samsun, Turkey. Our dialysis patients had similar social backgrounds, and the majority were from a moderate social class. All underwent dialysis for an average of 4 to 5 hours, 3 times per week. The patients were given an educational handout on TST the week before the testing started, and written consent for testing was obtained. Patient charts were reviewed for demographics (age, sex,
Results
The frequency of TB reactions and anergy were examined in 106 patients. The demographic characteristics are shown in Table 1. Initial tuberculin reactivity was classified into the following 3 ranges of induration: <5 mm (36.8%, n = 39), 5 to 10 mm (25.5%, n = 27), >10 mm (37.7%, n = 40). Reactivity to Candida was classified similarly: <5 mm (95%, n = 37), 5 to 10 mm (42.4%, n = 45), >10 mm (22.6%, n = 24).
Overall, 40 (37.7%) of the 106 patients had a significant tuberculin reaction (≥10 mm) on
Discussion
TB remains a significant health problem for patients receiving long-term HD. These patients are 6 to 16 times more likely to develop active TB than other members of their local community, especially in developing countries.2, 3, 13, 14, 17 Similarly, several studies have shown that the incidence of active TB disease is high among chronic HD patients in Turkey.2, 3, 14, 17 For that reason, there has been an increased awareness of the need to vigorously promote TB control measures, including
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