Coronary artery diseaseUsefulness of Self-Reported Leisure-Time Physical Activity to Predict Long-Term Survival in Patients With Coronary Heart Disease
Section snippets
Methods
The Coronary Artery Surgery Study (CASS) Registry includes 24,958 patients with suspected or proven CHD who were enrolled at 15 North American centers from 1974 to 1979.1 Patients had scheduled follow-up on an annual basis until 1982. Vital status was subsequently obtained through a mail-in survey completed from 1989 to 1991. Vital status for nonresponders was obtained from the National Death Index for patients in the United States and by next of kin, medical records, and death certificates in
Results
Decreasing physical activity level was associated with a higher proportion of women and older age and a higher prevalence of smoking, diabetes, hypertension, and family history of premature CHD (Table 1). Body mass index was similar between groups, although body weight was lower in less active individuals. As expected, higher physical activity level corresponded to better physical fitness. Fasting plasma glucose and triglycerides were also higher in less active subjects.
After a median long-term
Discussion
Our findings showed for the first time in a very large prospectively collected CHD cohort that self-reported leisure-time physical activity predicted both intermediate- and long-term clinical outcomes. In unadjusted models, a clear risk gradient was evident from the most to the least active groups, with a 1.6- to 2-fold increase in risk of major CV events in sedentary subjects. The impact of physical activity level on outcomes was similar for men and women. Adjusted models showed similar risk
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2020, Sleep MedicineCitation Excerpt :Prior research has provided support for both directions of the physical activity-sleep relationship, and researchers have argued that the association between these two variables is most likely reciprocal [50,61]. Second, although support for the validity of our physical activity assessment tool has been reported previously [40,62], the use of a 1-item self-report measure can be seen as a limitation [63]. Thus, the SGPALS is a rather crude measure of physical activity, which will create less variance than optimally wanted.
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2020, American Journal of CardiologyCitation Excerpt :However, this study focused on elderly patients (over 65) and adjustment in multivariate analysis does not include important variables such as left ventricular function and cardio-vascular risk factors. In 2008, Appullan et al, published data from the CASS Registry with a median follow-up of 14.7 years.18 Similarly to our study, their results demonstrated an independent correlation between the level of physical activity and long-term mortality.
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2018, American Journal of CardiologyCitation Excerpt :This overall effect on risk was also seen independently for energy expended in each of the 2 contexts of physical activity. A clear inverse dose-response relation between LTPA and all-cause mortality was observed, supporting findings of previous studies based on patients with coronary heart disease16 and myocardial infarction.17 In contrast, for DWPA, patients who had the lowest risk of all-cause mortality were those engaging in lower levels of DWPA (1 to 999 kcal/week) compared with the most active group of DWPA (1,000+ kcal/week).
Effect of Changes in Physical Activity on Risk for Cardiac Death in Patients With Coronary Artery Disease
2018, American Journal of CardiologyCitation Excerpt :The present results suggest that even small amounts and minor changes of LTPA affect cardiac mortality as well as total mortality. Despite the well-established prognostic significance of LTPA regarding all-cause and cardiovascular mortality in CAD,5,6,16 the present study provides important novel information regarding prognostic significance of the changes in LTPA that has not been extensively studied. In many previous clinical follow-up studies,5,6 LTPA has been quantified by single measurement following typical research setting applied in this type of study.