Clinical surgery-InternationalAssociation between persistent symptoms and long-term quality of life after laparoscopic total fundoplication
Section snippets
Materials and Methods
A total of 144 patients (78 males), with a mean age of 40.4 ± 15.1 years (range, 16–79 y) selected to undergo laparoscopic treatment for gastroesophageal reflux disease were included in the study after giving their informed consent. The study protocol was approved previously by the Ethical Committee of the Second University of Naples. All patients and controls were Caucasians from Italy.
Patients having typical or atypical symptoms for at least 6 months and requiring daily medical therapy for
Baseline
A total of 144 patients (78 males), with a mean age of 40.4 ± 15.1 years (range, 16–79 y) and with a mean duration of symptoms of 46.4 ± 47.3 months (range, 7–240 mo) before surgery, were enrolled in the study. All the patients survived. A conversion to an open procedure was required for respiratory troubles linked to pneumoperitoneum in 1 case (.7%). In 1 patient (.7%) an intraoperative mucosal tear occurred, which was repaired immediately by using 1 stitch and abdominal drainage, and no
Comments
The outcome of antireflux surgery traditionally has been evaluated by objective measurements (upper-gastrointestinal endoscopy, stationary esophageal manometry, and 24-hour ambulatory pH monitoring) that seem to have poor correlation with patient-perceived symptoms.16 From the patient's point of view, the so-called heuristic end points such as symptom resolution, patient satisfaction, patient well being, and quality of life are at least as important as objective tests, which are more invasive
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