Original articleAdult cardiacMaterial Properties of CorCap Passive Cardiac Support Device
Section snippets
Specimen Construction
In contrast to biological tissues being routinely tested on biaxial stretching systems, the CorCap CSD fabric has an open mesh structure that is not homogeneous and uniform. Therefore, if the CSD is tested alone, an uneven distribution of forces results, which in turn leads to a large amount of shear stress and deformation of the specimens. This open air mesh makes determination of mechanical properties using standard tensile testing methods unreliable without the development of additional
Results
Cauchy stress/Green strain curves for silicone specimens are depicted in Fig 3. The mechanical behavior of silicone specimens was completely linear as expected. It was consistent among the 4 different specimens as well as between the 2 orthogonal directions for each individual specimen, with an average stiffness of 2.57 MPa. Silicone specimens were stretched to a maximum extension of 10%, at which point the samples tore, mainly at the site of hook insertion. An average constant of 445 kPa was
Comment
Ventricular remodeling is 1 of the most important mechanisms of the progression of HF, independent of the patient's hemodynamic and neurohormonal status [4, 16, 17]. From the gross anatomic standpoint, alterations in left ventricular (LV) geometry leads to 4 major pathophysiologic consequences: LV chamber dilation, increased LV sphericity, LV wall thinning, and mitral valve incompetence [18]. As a result, LV wall stress dramatically increases during ventricular remodeling and places higher
References (29)
- et al.
Left ventricular shape, afterload and survival in idiopathic dilated cardiomyopathy
J Am Coll Cardiol
(1989) - et al.
Hemodynamics and myocardial blood flow patterns after placement of a cardiac passive restraint device in a model of dilated cardiomyopathy
J Thorac Cardiovasc Surg
(2011) - et al.
Determination of strain energy function for arterial elastin: experiments using histology and mechanical tests
J Biomech
(2007) - et al.
Beneficial effects of the CorCap cardiac support device: five-year results from the Acorn Trial
J Thorac Cardiovasc Surg
(2012) - et al.
Sustained benefits of the CorCap Cardiac Support Device on left ventricular remodeling: three year follow-up results from the Acorn clinical trial
Ann Thorac Surg
(2007) - et al.
One-year results after implantation of the CorCap for dilated cardiomyopathy and heart failure
Ann Thorac Surg
(2011) - et al.
Reverse remodeling and enhanced adrenergic reserve from passive external support in experimental dilated heart failure
J Am Coll Cardiol
(2002) - et al.
Early and late effects of passive epicardial constraint on left ventricular geometry: ellipsoidal re-shaping confirmed by electron-beam computed tomography
J Heart Lung Transplant
(2006) - et al.
Surgical treatment of advanced heart failure: alternatives to heart transplantation and mechanical circulatory assist devices
Prog Cardiovasc Dis
(2011) - et al.
Ventricular restraint therapy for heart failure: the right ventricle is different from the left ventricle
J Thorac Cardiovasc Surg
(2010)
Passive epicardial containment prevents ventricular remodeling in heart failure
Ann Thorac Surg
Postmortem examination of the CorCap device: macroscopic and microscopic findings
Cardiovasc Pathol
Heart failure
N Engl J Med
Heart disease and stroke statistics—2011 update: a report from the American Heart Association
Circulation
Cited by (7)
Thermoplastic polycaprolactone elastomer for a 3D-printed pericardial scaffold in the treatment of dilated cardiomyopathy
2022, BioprintingCitation Excerpt :Intervention with a pericardial scaffold 3D printed from the TPE could be less costly and less invasive than LVADs, syncardia, or heart transplants. There is a growing body of evidence suggesting that pericardial scaffolds can afford the heart the necessary rest to sufficiently recover [17,18]. In a recent canine study, a biodegradable heart wrap showed higher left ventricular ejection fractions (LVEFs) versus non-biodegradable controls over 12 weeks [19].
Cardiac mechanostructure: Using mechanics and anisotropy as inspiration for developing epicardial therapies in treating myocardial infarction
2021, Bioactive MaterialsCitation Excerpt :Two of the most extensively studied epicardial restraint devices are CorCap by Acorn and the HeartNet by Paracor. The Acorn CorCap, made by knitting polyester, features a unique geometry that provides bidirectional compliance, with greater support in the circumferential direction compared to the longitudinal direction (Fig. 1A) [130]. Preclinical studies in ovine models revealed improvement in global ventricular structure [127] and function [131] when treating tachycardia-induced HF as well as preserved cardiomyocyte length adjacent to infarcted myocardium when treating MI [132].
A bioresorbable biomaterial carrier and passive stabilization device to improve heart function post-myocardial infarction
2019, Materials Science and Engineering CCitation Excerpt :Adequate conformity of mechanical support devices with the healthy myocardium in terms of mechanical properties is essential to successfully transfer stress from the infarcted myocardium and border zone while preserving the native cardiac contractility [4,6,22]. However, former whole heart passive restraint devices [4] are characterized by a much higher stiffness than the native myocardium at the end of the systole, such as 500 kPa [22], and as a result impair diastolic function of the right ventricle [64]. Chitsaz, Wenk [64] determined that the CorCap device has a minimal stiffness of 3 MPa in its cross-fiber direction.
Biventricular finite element modeling of the acorn CorCap cardiac support device on a failing heart
2013, Annals of Thoracic SurgeryCitation Excerpt :Both sets of angles are based on previous measurements of the CSD [13]. We recently derived a material property law sufficient to describe the Acorn CSD fabric and measured material constants in silicone embedded fabric samples with a biaxial stretcher [14]. Those findings were implemented into LS-DYNA using the material routine *MAT_091 [8].
Artificial Muscles and Soft Robotic Devices for Treatment of End-Stage Heart Failure
2023, Advanced MaterialsSuccessful LVAD implantation and heart transplantation after ACORN corcap placement
2019, Journal of Cardiac Surgery