Elsevier

Brain Research

Volume 1098, Issue 1, 7 July 2006, Pages 126-128
Brain Research

Short Communication
Hyperbaric oxygen treatment decreases inflammation and mechanical hypersensitivity in an animal model of inflammatory pain

https://doi.org/10.1016/j.brainres.2006.04.088Get rights and content

Abstract

Hyperbaric oxygen therapy has been used to treat a variety of ailments from carbon monoxide poisoning to fibromyalgia. The purpose of this experiment was to explore the effect of hyperbaric oxygen treatment on carrageenan-induced inflammation and pain in rats. Hyperbaric oxygen treatment significantly decreased inflammation and pain following carrageenan injection. Clinically hyperbaric oxygen may be used in situations where NSAIDS are contraindicated or in persistent cases of inflammation.

Section snippets

Acknowledgments

The authors would like to thank Virginia Toepfer for performing the hyperbaric oxygen treatment and Dr. Yuan Bo Peng for insightful discussions regarding the project.

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