Cell
Volume 124, Issue 6, 24 March 2006, Pages 1111-1115
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Essay
Stem Cells and Cancer: Two Faces of Eve

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Recent evidence suggests that a subset of cancer cells within some tumors, the so-called cancer stem cells, may drive the growth and metastasis of these tumors. Understanding the pathways that regulate proliferation, self-renewal, survival, and differentiation of malignant and normal stem cells may shed light on mechanisms that lead to cancer and suggest better modes of treatment.

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