Cell
Volume 135, Issue 3, 31 October 2008, Pages 417-420
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Knockdown Screens to Knockout HIV-1

https://doi.org/10.1016/j.cell.2008.10.007Get rights and content
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Three recent screens use siRNAs to identify host genes that are critical for HIV-1 replication. These screens have uncovered hundreds of human genes not previously known to be commandeered by the virus during infection. Although some caveats remain, this screening approach opens up a new landscape of viral-host interactions for future exploration.

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