Cell
Volume 150, Issue 5, 31 August 2012, Pages 875-877
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Holding on through DNA Replication: Histone Modification or Modifier?

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Histone methylation is widely believed to contribute to epigenetic inheritance by persevering through DNA replication and subsequently templating methylation of daughter chromosome regions. However, a report in this issue (Petruk et al.) suggests that chromatin association of the methytransferase complexes themselves persists through replication and re-establishes histone methylation.

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