Metagenomic Approaches for Defining the Pathogenesis of Inflammatory Bowel Diseases

doi:10.1016/j.chom.2008.05.001

Cell Host & Microbe

Volume 3, Issue 6, 12 June 2008, Pages 417-427

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Summary

The human gastrointestinal tract is home to immense and complex populations of microorganisms. Using recent technical innovations, the diversity present in this human body habitat is now being analyzed in detail. This review focuses on the microbial ecology of the gut in inflammatory bowel diseases and on how recent studies provide an impetus for using carefully designed, comparative metagenomic approaches to delve into the structure and activities of the gut microbial community and its interrelationship with the immune system.

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³: These authors contributed equally to this work

⁴: Present address: Department of Food Science and Technology, University of Nebraska, Lincoln, NE 68583, USA

Cell Host & Microbe

ReviewMetagenomic Approaches for Defining the Pathogenesis of Inflammatory Bowel Diseases

Summary

Review
Metagenomic Approaches for Defining the Pathogenesis of Inflammatory Bowel Diseases