Developmental Cell
Volume 22, Issue 2, 14 February 2012, Pages 279-294
ArticleDistinct Phosphorylations on Kinesin Costal-2 Mediate Differential Hedgehog Signaling Strength
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Graphical Abstract
Highlights
► Distinct phosphorylation of Costal-2 depends on the magnitude of Smo activation ► The phosphoisoforms of Cos2 are differentially distributed inside the cell ► Cos2 dual phosphorylations promote high levels of Hh signal transduction
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These authors contributed equally to this work
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Present address: INRA, UMR6243 CNRS, Université de Nice-Sophia Antipolis, Nice 06108, France
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