To predict the cost of a delivery following assisted reproductive technologies (ART).
Design
Cost analysis based on retrospective chart analysis.
Setting
University-based ART program.
Patient(s)
Women aged ≥26 and ≤42 years with FSH levels ≤12 IU/L on day 3 undergoing a first cycle of fresh, nondonor ART.
Intervention(s)
Logit regression using a fractional polynomial model of age and basal FSH was used to estimate the probability of a live birth. Cost analysis was applied to the resulting prediction.
Main Outcome Measure(s)
The predicted probability of a live birth following ART based on a woman's age and FSH and the associated cost of a live birth.
Result(s)
Analysis of 1,238 first ART cycles produced a prediction model for live birth rates following ART incorporating both age and FSH. A cost analysis based upon combination of age and FSH revealed the cost of a live birth exceeded $100,000 when the probability of a live birth fell below 15% and the cost rose exponentially at lower probabilities of live birth.
Conclusions(s)
Based upon a woman's age and FSH and expected cost for a live birth using ART may be calculated. At live birth rates <5%, the cost of ART is high and greatly exceeds the cost of donor cycles. This information is vital for patient counseling.
Key Words
In vitro fertilization
cost analysis
assisted reproduction
FSH
age
IVF
ART
Cited by (0)
The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the department of the Army or the Department of Defense.
Supported, in part, by the intramural research program of the Reproductive Biology and Medicine Branch of NICHD, NIH.
