Letter to the Editor
Management of giant cell lesions

https://doi.org/10.1016/j.ijom.2006.08.010Get rights and content

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Cited by (15)

  • Multiple versus solitary giant cell lesions of the jaw: Similar or distinct entities?

    2021, Bone
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    Pharmacologic agents have shown to be promising alternatives to surgical management. Most authors consider this option only for the more recurrent aggressive lesions, taking potential side effects and discomfort of potential long duration of treatment into account [56]. Calcitonin is one of the most reported pharmacological treatments.

  • Complications of Dentoalveolar Surgery

    2020, Oral and Maxillofacial Surgery Clinics of North America
    Citation Excerpt :

    GCTs are characterized by a proliferation of fibroblast with various amounts of collagen with multinucleated giant cells dispersed throughout. A recent hypothesis is that these lesions be considered proliferative vascular in origin or angiogenesis-dependent (Fig. 3).75,76 Systemic disorders associated with an increased risk of bleeding are termed coagulopathies.

  • Surgical treatment of central giant cell granuloma in child and follow-up for 18 months

    2018, Pediatric Dental Journal
    Citation Excerpt :

    The defenders of this alternative treatment indicate that pharmacological agents decrease the recurrence rates, minimize the surgical morbidity or have the potential to prevent the need for surgical intervention [10]. Kaban and Dotson [15] argue that pharmacological agents should be used only in aggressive lesions due to the fact that they have adverse effects and that long-lasting treatment affects patient comfort. In this case, the surgical method that would affect the comfort of daily life for a shorter time was preferred because it would be a problem for the school-age child to come to our clinic frequently.

  • Pharmacological and surgical therapy for the central giant cell granuloma: A long-term retrospective cohort study

    2017, Journal of Cranio-Maxillofacial Surgery
    Citation Excerpt :

    Advocates of these alternative treatment regimens state that pharmacologic agents have the potential to decrease recurrence rates, while at the same time minimizing surgical morbidity or even preventing the need for surgical intervention. As this approach may be associated with side effects and the discomfort of a long duration of treatment, some authors have advocated their use only for aggressive lesions (Kaban and Dodson, 2006). However as previously mentioned, even in non-aggressive cases vital structures such as tooth buds and neurovascular bundles might be at risk.

  • Does a difference exist in inferior alveolar canal displacement caused by commonly encountered pathologic entities? An observational study

    2011, Journal of Oral and Maxillofacial Surgery
    Citation Excerpt :

    The most frequent location of vascular anomalies, similar to odontogenic origin tumors, is the molar and premolar regions of the posterior mandible.41 Most recently, the proposed hypothesis for central giant cell granuloma is that these lesions should be considered proliferative and vascular in origin or at least angiogenesis dependant.42-55 The present study is the first to have examined the potential differences in the displacement of the inferior alveolar neurovascular bundle caused by 2 commonly encountered pathologic entities in the maxillofacial region: odontogenic tumors and vascular anomalies.

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