ResearchResearch and Professional BriefAssessing Validity and Reliability of Resting Metabolic Rate in Six Gas Analysis Systems
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Subjects
Five men and seven women, all healthy, with an average age of 24±11 years and body mass index (BMI) of 21.8±2.1 were recruited from the University of Wisconsin–Madison through on-campus advertising to participate in a 2-day RMR study. The study was approved by the Institutional Review Board of the University of Wisconsin–Madison and informed written consent was obtained. Exclusion criteria included a history of metabolic or pulmonary disease, implanted electrical devices, and claustrophobia.
Internal Validity and Reliability of the DTC
Alcohol burn tests performed at the University of Wisconsin–Madision and Loyola University Medical Center tested the accuracy of the DTC. At the University of Wisconsin–Madison, burns revealed carbon dioxide at 98.9%±1.2% of theoretical and oxygen at 98.9%±1.1% of theoretical. Loyola University Medical Center burns yielded 101.9%±2.1% and 100.3%±0.9% of theoretical for carbon dioxide and oxygen, respectively. Correction factors developed based on these data were applied to DTC data from the
Conclusions
Because the DTC instrument is no longer being manufactured, another valid and reliable gas analysis system is needed. We compared five systems with the DTC and found that the TrueOne and the Vmax were the most valid gas analysis systems of those tested for measuring both RMR and RER relative to the DTC; however, none of the gas analysis systems tested can be considered adequately reliable for use in a research setting, although the TrueOne comes close. This is disappointing considering that the
J. A. Cooper is a graduate student, Department of Nutritional Sciences, University of Wisconsin–Madison, Madison, WI
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J. A. Cooper is a graduate student, Department of Nutritional Sciences, University of Wisconsin–Madison, Madison, WI
A. C. Watras is a research coordinator, Department of Nutritional Sciences, University of Wisconsin–Madison, Madison, WI
D. A. Schoeller is a professor, Department of Nutritional Sciences, University of Wisconsin–Madison, Madison, WI
M. J. O'Brien is pulmonary function lab manager, Pulmonary Lab, University of Wisconsin Hospital and Clinics, Madison, WI
A. Luke is an associate professor, Department of Preventive Medicine and Epidemiology, Loyola University, Maywood, IL
J. R. Dobratz is a graduate student, Department of Food Science and Nutrition, University of Minnesota, St Paul
C. P. Earthman is an assistant professor, Department of Food Science and Nutrition, University of Minnesota, St Paul