Letter to the EditorFighting MRSA in hospitals: time to restrict the broad use of specific antimicrobial classes?
References (8)
- et al.
Impact of restricting fluoroquinolone prescription on bacterial resistance in an intensive care unit
J Hosp Infect
(2005) - et al.
Impact of a 12-month fluoroquinolone (FQ) restriction on MRSA incidence in a French university hospital [abstract K-1743]
(2003) - et al.
Antimicrobial drug use and methicillin-resistant Staphylococcus aureus, Aberdeen, 1996—2000
Emerg Infect Dis
(2004) - et al.
Development of a strategy for decreasing multi-drug resistant bacteria with implementation of a program emphasizing appropriate antibiotic utilization and strict infection control measures in Western South Dakota
S D Med J
(2002)
Cited by (8)
MRSA bacteraemia
2007, International Journal of Antimicrobial AgentsCitation Excerpt :Another possible explanation for the increased risk of both serious infections, such as SAB, and death after acquisition of MRSA as opposed to MSSA concerns prior antibiotic use as a predisposition. While a recent Cochrane review provided no robust evidence that antibiotic stewardship interventions influence MRSA rates, there are now approaching a dozen papers [24] that provide plausible and consistent evidence that reduction of third-generation cephalosporin (3GC) and 4-fluoroquinolone (4FQ) prescribing can lead to reduced MRSA rates. Some of the more recent studies are of interrupted time series methodology which will be considered by Cochrane in its update.
Infections in nursing homes: The most frequent microorganisms, antimicrobial use and bacterial resistance
2007, Revista Espanola de Geriatria y GerontologiaAntibiotic resistance: Location, location, location
2007, Clinical Microbiology and InfectionCitation Excerpt :Even discounting such factors, there is still variation in MRSA bacteraemia rates when ostensibly similar acute-care general hospitals in England are compared with each other. Such variation must partly reflect relative attention to infection control and antibiotic usage patterns [24], although the roles of quinolones and cephalosporins in MRSA selection remain controversial [25,26], and a recent study found little correlation between visual cleanliness and the incidence of MRSA bacteraemias [27]. The other critical factor is case-mix: MRSA bacteraemias are rare among maternity and psychiatric patients and in infants, so that large units handling these patients will ‘dilute’ a hospital's rate, calculated as cases per 1000 bed-days across the whole site [21].
Efficacy of control measures to prevent MRSA transmission in health institutions. An up-dated view
2006, Enfermedades Infecciosas y Microbiologia ClinicaMethicillin-resistant Staphylococcus aureus (MRSA) in food production animals
2010, Epidemiology and InfectionLook to Norway - men hvor lenge?
2010, Tidsskrift for den Norske Laegeforening