Dupuytren’s contractureDupuytren’s Diathesis Revisited: Evaluation of Prognostic Indicators for Risk of Disease Recurrence
Section snippets
Study Sample
A hospital-based, retrospective, cohort study design was used to recruit patients with a diagnosis of DD. All patients were enrolled after surgical management for DD, ensuring that the diagnosis of DD was accurate. The presence of DD nodules, cords in the palmar or plantar fascia, with or without contraction of affected digits on examination, was used to confirm the diagnosis. A total of 322 Caucasian patients diagnosed with DD were identified via surgical records from a hospital in the
Observations
Of the 322 patients, 141 (44%) had recurrent (true recurrence) DD. Each patient had a fasciectomy for treatment of DD. The frequency of observed associated risk factors in all patients was documented (Table 1). Of note, ectopic lesions were found in 77 (24%) patients. There was no Peyronie’s disease, 41 (13%) had Garrod’s pads, and 36 (11%) had Lederhose’s lesions. Bilateral palmar DD lesions were apparent in 225 (70%) patients. A family history was reported by 143 (44%) patients. The mean age
Discussion
The odds ratio and predictive risk for developing recurrent DD after surgical management has been derived with an implication to modify the current DD diathesis. Patients with features of DD diathesis are at high risk for developing recurrence after treatment. In this study we observed true and false recurrences; those patients with a true recurrence and not a false recurrence or extension of DD were considered to have recurrent DD after surgical treatment.
It has been suggested that those with
References (38)
- et al.
Percutaneous needle aponeurotomy: complications and results
J Hand Surg
(2003) - et al.
The association between alcohol, hepatic pathology and Dupuytren’s disease
J Hand Surg
(1992) - et al.
The association between frozen shoulder and Dupuytren’s disease
J Shoulder Elbow Surg
(2001) Dupuytren’s disease—initial symptoms, age of onset and spontaneous course
Hand
(1977)- et al.
The incidence of Dupuytren’s disease in patients with rheumatoid arthritis
J Hand Surg
(1984) - et al.
Chromosomal abnormalities in Dupuytren’s contracture and carpal tunnel syndrome
J Hand Surg
(1992) - et al.
[Manual labor and Dupuytren diseaseThe results of a computerized survey in the field of iron metallurgy]
Ann Chir Main
(1983) Dupuytren’s disease: relation to work and injury
J Hand Surg
(1991)- et al.
An objective method to evaluate the risk of recurrence and extension of Dupuytren’s disease
J Hand Surg
(2004) - et al.
Long term follow-up of dermofasciectomy for Dupuytren’s contracture
Br J Plast Surg
(1994)
Unsatisfactory results in Dupuytren’s contracturePhilosophies of Dr. J. T. Hueston
Hand Clin
The heritability of Dupuytren’s disease: familial aggregation and its clinical significance
J Hand Surg
Epidemiology of Dupuytren’s disease: clinical, serological, and social assessmentThe Reykjavik study
J Clin Epidemiol
Knuckle pads in Dupuytren’s disease
Hand
Management of Dupuytren’s disease—clear advice for an elusive condition
Ann R Coll Surg Engl
Dupuytren’s disease
J Bone Joint Surg
Recurrences in Dupuytren’s contracture
Dupuytren’s diathesis; a case report
J Bone Joint Surg
Cited by (118)
The association between echogenicity and progression of Dupuytren's disease (DD): Birth of an imaging biomarker?
2023, Journal of Plastic, Reconstructive and Aesthetic SurgeryFull-thickness skin grafting in preventing recurrence of Dupuytren's disease: A systematic review
2023, Hand Surgery and RehabilitationAdvanced Dupuytren Contracture: Approach to Management
2023, Hand ClinicsPredicting complete finger extension in Dupuytren's disease
2022, Journal of Plastic, Reconstructive and Aesthetic SurgeryCitation Excerpt :In contrast, variables, such as age, sex, and family history, which are part of the so-called Dupuytren's diathesis,13 were not associated with complete finger extension after surgery. However, it is well known that these factors are associated with more aggressive forms of Dupuytren's disease and higher recurrence rates.13,14 Therefore, these factors are still important to take into consideration when discussing treatment options with patients.
Report on the Evidence-Based Practice Committee's Survey on Dupuytren Disease
2021, Journal of Hand Surgery Global OnlineCitation Excerpt :Moreover, the connection between alcohol misuse and bilateral or more advanced disease is even less clear—if there is a connection at all. However, 1 large series and other smaller epidemiologic studies report that women with a strong family history, patients with bilateral disease, and those with Ledderhose disease have the highest rates of aggressive and/or recurrent disease.18–22 While 70% of the respondents knew that PNA and CI have no differences in outcomes with regard to improvement in the range of motion, the vast majority of other respondents (28%) believed that CI has superior outcomes.
No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article.