Case ReportTenofovir-induced renal tubular dysfunction presenting with hypocalcaemia
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Cited by (13)
Chemico-physical investigation of tenofovir loaded polymeric nanoparticles
2012, International Journal of PharmaceuticsCitation Excerpt :Due to of its favorable resistance profile and activity against nucleoside-resistant HIV-1 strains, PMPA has been widely applied in therapy (Wainberg et al., 1999; Shirasaka et al., 1995). Some instances of both PMPA and PMPA DF toxicities were reported (hypophosphatemia and decrease of tubular phosphate reabsorption in HIV-positive adults (Badiou et al., 2006), renal tubular dysfunction presenting with hypocalcaemia (Williams and Chadwick, 2006), acute renal failure, Fanconi syndrome in AIDS patients (Malik et al., 2005) and fatal lactic acidosis (Giola et al., 2005)). These toxicities could be ascribed to the nephrolithiasis and hydronephrosis that might occur in an HIV-infected man receiving PMPA (Cicconi et al., 2004).
Antiviral drugs
2009, Side Effects of Drugs AnnualCitation Excerpt :The authors suggested that multiple drug interactions with tenofovir can lead to an increased risk of acute tubular necrosis and that frequent monitoring of renal function is warranted in any patients who are taking these combinations. Tenofovir has been associated with acute renal failure and Fanconi's syndrome(63A,64A). The risk seems to be increased in patients who are taking tenofovir concurrently with ritonavir, lopinavir+ritonavir, didanosine, or atazanavir.
Bone health and HIV in resource-limited settings: A scoping review
2016, Current Opinion in HIV and AIDSTenofovir-related Fanconi's syndrome and osteomalacia in a teenager with HIV
2013, BMJ Case Reports