Clinical StudyThe clinical characteristics of 2,789 consecutive patients in a memory clinic in China
Introduction
In Shanghai, people who were 65 years old or older accounted for 7.2% of the population in 1979, and this proportion increased to 19.6% by the end of 2005, primarily due to a decline in birth rate and longer life expectancy.1 To meet the increasing demand for the diagnosis and treatment of memory diseases in an aging society, the Neurology Department at Huashan Hospital formed its own Memory Clinic in 1996. Prior to March 2003, clinic patients had been tested using the Chinese version of the Mini-Mental State Examination (MMSE)2 and the Chinese version of the Wechsler Memory Scale-I (WMS-RC).3 Between 1999 and 2003, we tested the reliability and validity of a neuropsychological battery of tests (see methods) and established the cutoff values and age- and education-adjusted normative data in Shanghai. Since the first formal implementation of this assessment from April 2003 to April 2008, 2,789 patients have attended our Memory Clinic. To provide suggestions for future research, the demographic, cognitive and aetiological data of these patients were reviewed.
Section snippets
Patients
This study reviewed the data from 2,789 consecutive patients of the Memory Clinic of Huashan Hospital from April 2003 to April 2008. Most of the patients noticed cognitive decline and presented to the clinic of their own accord. The other patients, most of whom were illiterate or old, were referred by their caregivers.
Diagnostic assessment
The basic diagnostic flowchart is shown in Fig. 1. For all patients, the MMSE, neurological physical examinations, psychiatric evaluations, including anxiety and depression
The demographic characteristics of the 2,789 patients
The demographic characteristics of the 2,789 patients are shown in Fig. 2. There were more females (58%) than males. Most of the patients (about 92%) were literate; 15% were educated for 1 to 5 years, 23% for 6 to 8 years, 30% for 8 to 12 years, and 24% for more than 12 years. Another subset of patients (8%) did not receive any education. The distribution of patients in the various age groups was as follows: 145 (5.2%) were less than 50 years old, 415 (14.9%) were between 50 and 59 years old,
Discussion
In this study we report the demographic, cognitive and aetiological data from 2,789 consecutive patients who attended the Memory Clinic of the Department of Neurology at Huashan Hospital from April 2003 to April 2008. The data we report here do not represent entirely the general elderly population in China. First, the Memory Clinic is located in the centre of Shanghai, and most of the participants lived near the hospital, so they did not qualify as a random sample of a community
Acknowledgements
The study is supported by The Natural Science Foundation of China (number: 30570601) and Science and Technology Commission of Shanghai Municipality (08411951000, 09DZ1950400).
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2021, National Medical Journal of China