Current best evidenceClinical research abstract for pediatricianAlternating ibuprofen and acetaminophen may be more effective in the treatment of fever in children
Clinical research abstract for pediatrician
Section snippets
Sarrell EM, Wielunsky E, Cohen HA. Antipyretic treatment in young children with fever: Acetaminophen, ibuprofen, or both alternating in a randomized, double-blind study. Arch Pediatr Adolesc Med 2006;160:197-202
Question Among young children aged 6 to 36 months with fever, does an alternating regimen of acetaminophen and ibuprofen have an improved antipyretic effect compared with either drug alone?
Design Randomized, double-blind, parallel-group trial.
Setting Three primary pediatric community ambulatory centers in Israel.
Participants 464 children, aged 6 to 36 months, with fever.
Intervention Infants were assigned to receive either acetaminophen (12.5 mg/kg per dose every 6 hours) (n = 154) or ibuprofen
Reference (1)
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Cited by (0)
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