Molecular Cell
Volume 48, Issue 1, 12 October 2012, Pages 75-86
ArticleProcessive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI
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Highlights
► Myosin VI uses a kinesin-like mechanism to step ► Compliance in the lever arm lead head is essential to attach strongly to actin ► Myosin VI does not move using a simple swinging lever arm mechanism
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These authors contributed equally to this work
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Present address: Laboratoire d'Enzymologie et Biochimie Structurales, Centre de Recherche de Gif, CNRS, 91198 Gif-sur-Yvette, France
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