Glossary
Base excision repair: a type of DNA repair whereby an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.
Cmax: a pharmacokinetic term describing the peak blood plasma concentration of a drug.
Clearance: a pharmacokinetic term representing the volume of plasma cleared of the drug per