Herpes simplex virus infection causes cellular β-amyloid accumulation and secretase upregulation
Section snippets
Acknowledgements
We thank Mrs. A. Cookson for initial and Ms. A. Frost for subsequent excellent technical assistance, Prof. M. Esiri (University of Oxford) and Dr. S. Efstathiou (University of Cambridge) for HSV1-infected mouse brain sections, Dr. Marcus Hughes (Aston University) for the U87MG and T98G glioblastoma cells, Prof. N. Hooper and Dr. E. Parkin (University of Leeds) for the APP-transfected SHSY5Y neuroblastoma cells, Dr. J. Powell, Unilever Corporate Research at Sharnbrook, Beds, UK, and the
References (25)
- et al.
Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice
Neuron
(2005) - et al.
Macrophages and microglia in HSV-1 infected mouse brain
J. Neuroimmunol.
(1995) - et al.
Herpes simplex virus type 1 in brain and risk of Alzheimer's disease
Lancet
(1997) - et al.
Herpes simplex virus type 1, apolipoprotein E, and cholesterol: a dangerous liaison in Alzheimer's disease and other disorders
Prog. Lipid Res.
(2006) - et al.
Nectin-1alpha, an immunoglobulin-like receptor involved in the formation of synapses, is a substrate for presenilin/gamma-secretase-like cleavage
J. Biol. Chem.
(2002) - et al.
Chlamydia pneumoniae induces Alzheimer-like amyloid plaques in brains of BALB/c mice
Neurobiol. Aging
(2004) - et al.
Abeta production as consequence of cellular death of a human neuroblastoma overexpressing APP
FEBS Lett.
(2004) - et al.
Apolipoprotein E-epsilon 4 protects against severe liver disease caused by hepatitis C virus
Hepatology
(2002) - et al.
Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides
J. Virol.
(2003) - et al.
Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis
Proc. Natl. Acad. Sci. U.S.A.
(2004)
Fibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's A beta peptide
Biochemistry
(2000)
The receptor-binding region of human apolipoprotein E has direct anti-infective activity
J. Infect. Dis.
(2006)
Cited by (263)
Recent insights into viral infections as a trigger and accelerator in alzheimer's disease
2022, Drug Discovery TodayPotential Involvement of Varicella Zoster Virus in Alzheimer's Disease via Reactivation of Quiescent Herpes Simplex Virus Type 1
2024, Advances in Alzheimer's DiseasePeripheral inflammation is a potential etiological factor in Alzheimer's disease
2024, Reviews in the NeurosciencesClinical evidence of human pathogens implicated in Alzheimer’s disease pathology and the therapeutic efficacy of antimicrobials: an overview
2023, Translational Neurodegeneration
Copyright © 2007 Elsevier Ireland Ltd. All rights reserved.