An inducible nitric oxide synthase polymorphism is associated with the risk of recurrent depressive disorder
Research highlights
▶ NOS2A gene is related to depression. ▶ Functional polymorphism −1026C/A of the NOS2A affects depression. ▶ The C allele and CC homozygote in −1026C/A are positive risk factors for depression.
References (49)
- et al.
NO synthase-II is transiently expressed in embryonic mouse olfactory receptor neurons
Neurosci. Lett.
(1997) - et al.
Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene
J. Biol. Chem.
(1994) - et al.
Inducible nitric oxide synthase appears and is co-expressed with the neuronal isoform in interneurons of the rat hippocampus after transient ischemia induced by middle cerebral artery occlusion
Exp. Neurol.
(2008) - et al.
Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment
Pharmacol. Rep.
(2009) - et al.
Nitric oxide, mitochondria and neurological disease
Biochim. Biophys. Acta
(1999) - et al.
Depressed new neurons-adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression
Biol. Psychiatry
(2003) - et al.
Norepinephrine and nitric oxide promote cell survival signaling in hippocampal neurons
Eur. J. Pharmacol.
(2010) - et al.
A novel, nerve growth factor-activated pathway involving nitric oxide, p53, and p21WAF1 regulates neuronal differentiation of PC12 cells
J. Biol. Chem.
(1997) - et al.
Nitric oxide-soluble guanylyl cyclase signaling regulates corticostriatal transmission and short-term synaptic plasticity of striatal projection neurons recorded in vivo
Neuropharmacology
(2010) - et al.
Cellular changes in the postmortem hippocampus in major depression
Biol. Psychiatry
(2004)
Nitric oxide fully protects against UVA-induced apoptosis in tight correlation with Bcl-2 up-regulation
J. Biol. Chem.
(1999)
Elevated plasma nitrate levels in depressive states
J. Affect. Disord.
(2001)
Free radicals and antioxidants in normal physiological functions and human disease
Int. J. Biochem. Cell. Biol.
(2007)
Prevention of chronic stress-induced depression-like behavior by inducible nitric oxide inhibitor
Neurosci. Lett.
(2008)
Local, but not systemic, administration of serotonergic antidepressants decreases hippocampal nitric oxide synthase activity
Brain Res.
(2003)
Peroxynitrite versus hydroxyl radical: the role of nitric oxide in superoxide dependent cerebral injury
Ann. N. Y. Acad. Sci.
(1994)
Statistics notes, the odds ratio
BMJ
(2000)
Nitric oxide and the immune response
Nat. Immunol.
(2001)
Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses
J. Immunol.
(2009)
Mechanisms of inflammatory neurodegeneration: iNOS and NADPH oxidase
Biochem. Soc. Trans.
(2007)
Implication of glutamate in the expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices
J. Neurochem.
(2000)
A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples
Biotechniques
(1993)
Tumor necrosis factor-alpha and phorbol 12-myristate 13-acetate differentially modulate cytotoxic effect of nitric oxide generated by serum deprivation in neuronal PC12 cells
J. Neurochem.
(1999)
The selective serotonin reuptake inhibitor fluoxetine reduces striatal in vivo levels of voltammetric nitric oxide (NO): a feature of its antidepressant activity?
Neurosci. Lett.
(2009)
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