Original articleEvaluation of Trabeculectomy Blebs Using 3-Dimensional Cornea and Anterior Segment Optical Coherence Tomography
Section snippets
Patients and Methods
We retrospectively examined 38 filtering blebs in 31 patients who had undergone trabeculectomy. They were recruited from the consecutive cases seen at the glaucoma clinic of Tsukuba University Hospital. All the patients were of Asian origin with a heavily pigmented iris. The patients comprised 25 males and 6 females in the age range of 20 to 79 years (mean±standard deviation, 57.8±13.9 years). There were 9 eyes with primary open-angle glaucoma, 3 eyes with primary angle-closure glaucoma, 12
Results
Representative photographs and 3-D CAS OCT images of the successful and failed blebs are shown in Figure 2, Figure 3. The microcysts, internal fluid-filled cavity, hyporeflective area, and scleral flap are delineated clearly. The well-functioning blebs exhibited a relatively thick wall, a large internal fluid-filled cavity, and many microcysts. In contrast, the nonfunctioning blebs exhibited a thin wall, a small or no internal fluid-filled cavity, and no microcysts. As shown in Figure 4, the
Discussion
In the present study, the internal morphologic features of filtering blebs were examined by using 3-D CAS OCT. As shown in Figure 1, Figure 2, Figure 3, the microcysts, internal fluid-filled cavity, and scleral flap were visualized clearly by 3-D CAS OCT. The scleral flap and aqueous humor drainage route in the bleb could be detected in more than 90% of the cases. In the successful bleb groups particularly, the scleral flap and aqueous drainage route in the bleb were detected in all eyes. These
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Manuscript no. 2008-651.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Supported in part by the Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research no.: 19791256), Tokyo, Japan.