Original articleClinical Characteristics and Visual Outcome of Severe Ocular Chemical Injuries in Shanghai
Section snippets
Methods
We reviewed the medical records of patients in our unit from 1998 to 2008. The Medical Ethics Committee of Shanghai Eye, Ear, Nose, and Throat Hospital approved the study protocol.
Severe ocular chemical injury was defined as any person sustaining an injury with9 total loss of the corneal epithelium, corneal haziness obscuring iris detail or worse, and over 120° of limbal ischemia. These findings equate to grades 3 or 4 on the Hughes–Roper–Hall classification scale. All patients included in the
Shanghai Prevalence Rate of Severe Chemical Corneal Injury
During the study period, the Shanghai Ocular Chemical Injury Study (SOCIS) used a reporting base of approximately 79 525 medical records. From 1998 to 2008 inclusive, the SOCIS received 357 reports of patients with ocular chemical injury. Of these, 72 did not meet the inclusion criteria, and 95 injured <1 month before the end of the collection period. Therefore, there were 190 patients who were suitable for multivariate logistic regression analysis for potential factors associated with visual
Discussion
Eye injury is a major cause of blindness in China.10 The annual incidence of eye injury in Hong Kong is estimated to be approximately 125 cases per 100 000 people.11 Although ocular chemical injuries are considered to account for a significant percentage of eye injury, little information is available concerning the risk factors. Thus, determination of these risk factors has important public health implications. However, information about the epidemiology, clinical characteristics, management
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Manuscript no. 2009-1525.
Financial Disclosure(s): The authors have no proprietary or commercial interest in any of the materials discussed in this article.
Supported by grants from the Key Clinic Medicine Research Program, the Ministry of Health, China (2007–2009); Shanghai Excellent Leading Scholars Program, Science and Technology Commission of Shanghai Municipality, Shanghai (10XD1401100); Outstanding Doctoral Research Program Fudan University (2009–2011). The sponsor or funding organization had no role in the design or conduct of this research.