ReviewThe use of whole genome amplification in the study of human disease
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Abbreviations
WGA, whole genome amplification
PCR, polymerase chain reaction
PEP, primer extension preamplification
DOP-PCR, degenerate oligonucleotide primed PCR
LMP, ligation mediated PCR
SDA, strand displacement amplification
TLAD, T7-based linear amplification of DNA
LCM, laser capture microdissection
IRS, interspersed repetitive sequence
LA-PCR, linker adapter technique PCR
LL-DOP-PCR, long products from low DNA quantities DOP-PCR
I-PEP, improved PEP
CGH, comparative genomic hybridization
SNP, single nucleotide polymorphism
SSCP, single stranded conformational polymorphism
RFLP, restriction fragment length polymorphism
EFPE, ethanol-fixed paraffin embedded
FFPE, formalin-fixed paraffin embedded
LOH, loss of heterozygosity
TSG, tumour suppressor genes
SCOMP, single cell comparative genomic hybridization
PRSG, PCR of randomly sheared genomic
MDA, multiple displacement amplification
RCA, rolling circle amplification
Keywords
Whole genome amplification
PEP
DOP-PCR
SCOMP
SDA
TLAD
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