Original articleSurgically induced weight loss, including reduction in waist circumference, is associated with improved pulmonary function in obese patients
Section snippets
Study population
We evaluated patients aged 18–65 years who had a BMI >37 kg/m2 or a BMI of 32–37 kg/m2 with obesity-related co-morbidities. The patients who underwent bariatric surgery at the international endoscopic obesity center of the E-Da Hospital in Southern Taiwan from July 2007 to December 2008 were enrolled in the present study. All obese patients received the same modality of bariatric surgery (laparoscopic Roux-en-Y gastric bypass), and the surgical procedure has been previously described in full
Participant characteristics
From July 2007 to December 2008, 139 consecutive obese Chinese patients underwent bariatric surgery at the obesity center of E-Da Hospital in Southern Taiwan. Of these 139 patients, 30 were excluded because of incomplete PFTs during follow-up and 15 because of inadequate performance of the PFTs at baseline or follow-up. Of the 94 participants, women were predominant (62%), and the age range was 18–59 years (mean 31.2 ± 9.8). A history of smoking was noted in 26% of the patients. None of the
Discussion
The major finding of the present study was that all the anthropometric parameters of obesity, including BW, BMI, WC, HC, WHtR, and WHR, were significantly reduced 3 months after bariatric surgery. The PFT parameters also improved significantly. After adjustment for potential confounding factors, including age, gender, and smoking history, dWC correlated with dFEV1 and dFVC, and dBW correlated with dDLCO. These results indicate that pulmonary function can be improved after bariatric surgery in
Conclusion
Just as in previous studies, surgically induced weight loss was associated with improved pulmonary function. Through careful analysis of the relationship between the changes in the anthropometric parameters and the changes in PFT parameters, this improvement correlated best with a decreased WC and perhaps a decreased intra-abdominal pressure.
Disclosures
The authors have no commercial associations that might be a conflict of interest in relation to this article.
Acknowledgment
This study was supported by E-Da hospital grant E-MRP-096-051.
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