Renal transplantationOutcomeDeceased Donor Kidney Transplantation in Elderly Patients: Is There a Difference in Outcomes?
Section snippets
Methods
We conducted a retrospective analysis of a prospectively collected database of all deceased donor (DD) kidney transplants performed in adult recipients at Massachusetts General Hospital from January 1, 1998, through December 31, 2005. The only exclusions were pediatric patients (<20 years of age), simultaneous kidney–pancreas transplantation, other multi-organ transplants (heart–kidney, liver–kidney), and living donor kidney allograft recipients. A total of 271 DD kidney transplants met the
Results
Of the 76 patients (28.1%) who were >60 years old, 25 (32.1%) received ECD, 14 DCD, and 37 SCD kidneys. Of 195 younger recipients, only 35 (17.9%) received ECD kidneys (P < .001).
Donor, recipient, and allograft characteristics are summarized in Table 1. Because there were more older recipients who received ECD allografts, donor age was higher in these patients and more donors had a history of hypertension. However, donor body mass index (BMI) donor terminal SCr levels, and cold ischemia times
Discussion
According to the US Census Bureau, Americans in the 65–84 years of age range constituted 10.9% of the population in 2000; by 2050, they are projected to make up 15.7%.5 The demographics of ESRD demonstrate a constant increase in the age of new patients starting renal replacement therapy every year.1 With the aging of the American population, further growth in the population of elderly patients with ESRD is clearly anticipated. Approximately 160,000 patients in the United States >65 years (and
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Cited by (5)
Clinical Outcomes of Older Kidney Transplant Recipients
2021, American Journal of the Medical SciencesCitation Excerpt :There is technically no age limit to kidney transplantation. Saidi et al.3 reported that deceased donor kidney transplant recipients older than 60, when carefully selected based on physiologic, cardiovascular, and functional status, had comparable perioperative morbidity, mortality, incidence of delayed graft function, length of hospital stay, and rate of readmission compared to their younger counterparts. However, most other studies report that although patients above the age of 60 continue to derive survival benefit from being transplanted compared to remaining on the waitlist,4 they experience higher mortality than their younger counterparts while on the waitlist.5
Medicare immunosuppressant coverage and access to kidney transplantation: A retrospective national cohort study
2012, BMC Health Services ResearchManagement of end-stage renal disease in the older adult: Recent advances and future challenges
2009, Clinical GeriatricsKidney transplantation in the elderly
2009, Current Opinion in Organ Transplantation