Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
Oral and maxillofacial pathologySialolipoma: Report of two cases and review of the literature
Section snippets
Case 1
An 84-year-old female presented to an oral and maxillofacial surgeon for evaluation of a mass on her left buccal mucosa. Clinical examination revealed a mass measuring 1.0 x 1.0 cm on the left buccal mucosa. Excisional biopsy was performed and sent to the oral and maxillofacial pathology laboratory at the Mount Sinai Medical Center. The clinical impression was that of a minor salivary gland tumor—either a pleomorphic adenoma or possibly a low-grade mucoepidermoid carcinoma.
Histopathologic
Discussion
Although lipoma is a common soft tissue tumor, it rarely occurs in the salivary glands.1, 6, 7, 9, 10, 11 The sialolipoma is believed to be a lipoma with secondary entrapment of normal salivary gland elements.1 Nagao et al.1 examined 2051 cases of salivary gland tumors and found the incidence of conventional lipoma and sialolipoma to be 0.5% and 0.3%, respectively.1
In the breast, thyroid, parathyroid, skin, and thymus, tumors exhibiting a well-circumscribed mass composed of lipomatous elements
Conclusion
Sialolipomas are lipomas containing secondary entrapment of normal salivary gland acini and ducts.1 They can be differentiated from conventional lipomas microscopically because they contain entrapped normal salivary gland elements. Sialolipomas share similar clinical features with conventional lipomas of the salivary glands (e.g., the patients’ wide age range, a male predominance, and the presence of a slow-growing symptom-free mass).1, 6, 7 The clinical impression, in most cases of
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Histopathology
Cited by (23)
A rare case of recurrent congenital sialolipoma of parotid gland in a 3‑year‑old child: A case report and review of literature
2021, International Journal of Surgery Case ReportsLipomas of the submandibular space: Case report of a sialolipoma and review of diagnostic investigations available
2015, Journal of Oral and Maxillofacial SurgerySialolipoma of the salivary gland: Two new cases, literature review, and histogenetic hypothesis
2011, Journal of Oral and Maxillofacial SurgerySialolipoma of minor salivary glands
2011, Annals of Diagnostic PathologyCitation Excerpt :Some cases of sclerosing polycystic adenosis, a recently described entity, may present a prominent lipomatous stroma [27]. According to Ramer et al [6], sclerosing polycystic adenosis should be included in the differential diagnosis of sialolipomas, particularly when sampling adequacy is less than optimal. In contrast to sclerosing polycystic adenosis, no proliferation of ductal or acinar cells is observed in sialolipomas [6].
Sialolipoma of the palate: a rare case and review of the literature
2009, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and EndodontologyCitation Excerpt :The Ki-67 labeling index (LI) of sialolipoma, palatal gland, and pleomorphic adenoma was 1.27 (SD, 0.42), 1.42 (SD, 0.61), and 4.86 (SD, 2.87), respectively. Although lipoma is a common soft tissue tumor, oral lipoma, especially salivary gland lipoma, is rare.1,3 Lipoma in the salivary glands accounts for less than 0.5% of all parotid gland tumors, and several distinct histological variants, such as angiolipoma, fibrolipoma, pleomorphic lipoma, and spindle-cell lipoma, have been documented.
Hamartomatous sialolipoma of the submandibular gland: case report
2008, British Journal of Oral and Maxillofacial SurgeryCitation Excerpt :In 2001 Nagao et al. proposed the term “sialolipoma” to describe a distinct type of lipoma of the salivary gland that is composed of mature adipocytes and normal salivary gland tissue.1 We have been able to find only 17 similar case reports of this rare tumour in the English language.2–9 A 77-year-old woman was referred to our unit for investigation of a painless swelling in the right submandibular region that had been present for some months.