DNA immunization in combination with effective antiretroviral drug therapy controls viral rebound and prevents simian AIDS after treatment is discontinued
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Abbreviations
ART
antiretroviral therapy
HAART
highly active antiretroviral therapy
PMPA
[R]-9-[2-phosphonylmethoxypropyl]adenine
HBcAg
hepatitis B virus core antigen
PMED
particle-mediated epidermal delivery
PBMC
peripheral blood mononuclear cells
LPR
lymphoproliferative response
CTL
cytotoxic T lymphocyte
Keywords
Immunotherapy
Antiretroviral therapy
DNA vaccine
SIV AIDS
Cited by (0)
- 1
Current address: Department of Molecular Genetics and Biochemistry, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.
- 2
Current address: Chiron Corporation, Emeryville, CA, USA.
- 3
Current address: EMD Biosciences, Inc., Madison, WI, USA.
- 4
Current address: Recombiworks, Cranberry, PA, USA.
- 5
Current address: Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
- 6
Current address: Department of Biological Sciences, California State University - San Marcos, San Marcos, CA 92096, USA.
- 7
Current address: Ligocyte Pharmaceuticals, Inc., Bozeman, Montana, USA.
Copyright © 2005 Elsevier Inc. All rights reserved.