Short CommunicationInformation for the Coordinates of Exons (ICE): a human splice sites database
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Acknowledgments
We thank the staff at National Center for Biotechnology Information's LocusLink and help desk (Kim Pruitt, Peter Cooper, Vyvy Pham, Barbara Ruef, etc.) for their patience and assistance. We also thank the reviewers for their valuable comments and suggestions.
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Cited by (26)
MCL-1V, a novel mouse antiapoptotic MCL-1 variant, generated by RNA splicing at a non-canonical splicing pair
2010, Biochemical and Biophysical Research CommunicationsCitation Excerpt :We also revealed that Mcl-1V mRNA is generated by splicing within the first coding exon of Mcl-1 gene at a non-canonical donor–acceptor pair (GG–TG). According to the Information for the Coordinates of Exons (ICE): a human splice sites database [22], the GG–TG pair is rare but is utilized for a splice site. It has been suggested that the N-terminus of MCL-1L is important for the intracellular localization and the antiapoptotic function [21].
De Novo ABCD1 Gene Mutation in an Indian Patient With Adrenoleukodystrophy
2008, Pediatric NeurologyCitation Excerpt :Of the 3′ splice-site mutations, 87% involve the invariant AG dinucleotide, with an excess of mutations at position −2 in the intervening sequence [6]. Moreover, A is the preferred first nucleotide in the acceptor dinucleotide pair in splicing [7]. The present report describes an Indian patient with a 3′ splice-site mutation at the preferred first nucleotide (position −2) in the intervening sequence 4 of the ABCD1 gene.
Characterization of a half-size ATP-binding cassette transporter gene which may be a useful marker for ivermectin selection in Onchocerca volvulus
2006, Molecular and Biochemical Parasitology
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These authors contributed equally to this work.