Case ReportPregnancy following recurrent angiosarcoma of the ovary—A case report and review of literature
Introduction
Soft tissue sarcomas account for less than 1% of all malignancies. Angiosarcomas comprise only 2% of all soft tissue sarcomas. Approximately 20 cases of angiosarcoma of the ovary are documented in MEDLINE. There is no known case of complete remission lasting more than 48 months following recurrence of ovarian angiosarcoma, and, to our knowledge, the case we are reporting is the only instance of a successful pregnancy following this rare and fatal cancer.
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Case report
A 28 year old nulliparous woman on the oral contraceptive pill presented with acute right sided lower abdominal pain. An ovarian cyst with solid components was visualized on a diagnostic scan and a diagnosis of torsion of a dermoid cyst was made. An emergency laparotomy was performed, and a 20 × 25 cm right ovarian mass was found and right salpingo-oopherectomy carried out. The left ovary and tube and the uterus were entirely normal.
The histology of the ovary showed a variable appearance with
Discussion
Soft tissue sarcomas account for less than 1% of all cancers [1] and angiosarcomas comprise just 2% of all soft tissue sarcomas. They may occur in any region of the body but 60% arise in the skin and superficial soft tissues, predominantly in the head and neck region [1]. Angiosarcomas of the female reproductive system are very rare. They have most frequently been reported in the uterus and less commonly in the vagina, vulva, cervix and ovary. Overall, prognosis is poor and the reported 5-year
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