Elsevier

Environmental Research

Volume 21, Issue 1, February 1980, Pages 48-55
Environmental Research

Present knowledge of the toxic effect of beryllium
Mortality study of beryllium industry workers occupational lung cancer

https://doi.org/10.1016/0013-9351(80)90007-9Get rights and content

Abstract

A cohort of 3685 white males employed during 1937–1948 in two major industries manufacturing beryllium was followed to the end of 1976 to evaluate lung cancer mortality experience. Lung cancer mortality among beryllium-exposed workers was contrasted with that of workers employed in the viscose rayon industry. Study results demonstrated that lung cancer mortality among beryllium-exposed workers was significantly greater than that expected on the basis of lung cancer mortality experience of workers in the viscose rayon industry having similar employment patterns. The results of the present study are consistent with earlier animal bioassay studies and recent epidemiologic studies indicating that beryllium is carcinogenic. The results of the present study are not consistent with speculation attributing the excessive lung cancer mortality among beryllium-exposed workers to personal characteristics of individuals having unstable employment patterns.

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Supported by Research Contract 390/7-9277552/3919 from the National Institute for Occupational Safety and Health.

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