Original articleRisk factors for lung cancer in Rio de Janeiro, Brazil: a case-control study
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Meat consumption and risk of lung cancer: Evidence from observational studies
2012, Annals of OncologyCitation Excerpt :In subgroup analyses (Table 1), the results were fairly consistent with the overall summary measure when the analyses were restricted to high-quality studies and stratified by study design and histologic type; however, the positive association was not statistically significant in studies that adjusted for fruit and vegetable intake or in those that adjusted for the BMI. Sensitivity analysis by removing each study separately showed that excluding the study by Dosil-Diaz et al. [29] resulted in the highest summary estimate (RR = 1.45, 95% CI 1.19–1.76), while excluding the study by Shen et al. [28] resulted in the lowest summary estimate (RR = 1.26, 95% CI 1.02–1.56); sensitivity analysis where we omitted two studies [18, 20] that reported the risk estimates for lung cancer mortality rather than incidence showed similar results (RR = 1.33, 95% CI 1.05–1.70); sensitivity analysis in studies with the similar categories of total meat [16, 19, 33, 34, 38, 42] revealed that persons consuming meat >3 times per week had a RR of 1.29 (95% CI 1.02–1.63) compared with those consuming <2 times per week. Our analysis of 18 studies on red meat consumption and lung cancer yielded a summary RR of 1.34 (95% CI 1.18–1.52) (Figure 3).
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