Genotoxicity of haloalkene and haloalkane glutathione S-conjugates in porcine kidney cells
References (31)
- et al.
Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: a possible explanation for its nephrocarcinogenicity in male rats
Biochem. Pharmac.
(1986) - et al.
Bacterial β-lyase mediated cleavage and mutagenicity of cysteine conjugates derived from the nephrocarcinogenic alkenes trichloroethylene, tetrachloroethylene and hexachlorobutadiene
Chemico.-Biol. Interactions
(1986) - et al.
Renal processing of glutathione conjugates; role in nephrotoxicity
Biochem. Pharmac.
(1984) - et al.
Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity
Biochem. Pharmac.
(1986) - et al.
Structure/activity studies on the nephrotoxic and mutagenic action of cysteine conjugates of chloro- and fluoroalkenes
Chemico.-Biol. Interactions
(1985) - et al.
Use of isolated kidney cells for study of drug metabolism
Biochem. Pharmac.
(1979) - et al.
Result of a two-year chronic study with hexachlorobutadiene in rats
Am. ind. Hyg. Ass. J.
(1977) - et al.
Technical Report No. 232
- et al.
The transport of S-cysteine conjugates in LLC-PK1 cells and its role in toxicity
Molec. Pharmac.
(1986) - et al.
Characterization of an unscheduled DNA synthesis assay with Syrian hamster embryo cells
Mutation Res.
(1984)
Interactions of S-(1-haloethyl)-mercapturic acid analogs with plasmid DNA
Toxic. appl. Pharmac.
(1985)
Characterisation of an unscheduled DNA synthesis assay with a cultured line of porcine kidney cells (LLC-PK1)
Mutagenicity of hexachloro-1,3-butadiene and its S-conjugates in the Ames test—role of activation by the mercapturic acid a pathway in its nephrotoxicity
Carcinogenesis
(1988)
The inhibition of γ-glutamyltranspeptidase from human pancreatic carcinoma cells by (αS,5S)-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501)
Res. Commun. chem. Path. Pharmac.
(1980)
Biosynthesis and metabolism of glutathione S-conjugates to toxic forms
CRC Crit. Rev. Toxicol.
(1988)
Cited by (25)
Formation and Fate of Nephrotoxic and Cytotoxic Glutathione S-Conjugates: Cysteine Conjugate β-Lyase Pathway
1994, Advances in PharmacologyBioactivation of nephrotoxins and renal carcinogens by glutathione S-conjugate formation
1993, Toxicology LettersGlutathione conjugate mediated toxicities
1990, Toxicology and Applied PharmacologyBiosynthesis, bioactivation, and mutagenicity of S-conjugates
1990, Toxicology LettersBioactivation of hexachlorobutadiene by glutathione conjugation
1990, Food and Chemical ToxicologyRenal proximal tubular cells in suspension or in primary culture as in vitro models to study nephrotoxicity
1990, Chemico-Biological Interactions
Copyright © 1989 Published by Elsevier Ltd.