Cancer Letters

Cancer Letters

Volume 3, 1977, Pages 231-235
Cancer Letters

Investigations on the carcinogenic burden by air pollution in man the effect of a single dose of benzo(a)pyrene in Syrian golden hamsters

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Summary

Syrian golden hamsters received 4, 8 or 16 mg of benzo(a)pyrene (BP) in suspensions of 0.9% physiological saline or This buffer as a single intratracheal instillation. Neither survival time nor tumour incidence was dose dependent. The highest incidence of respiratory tract tumours was seen in male hamsters receiving 8 mg BP suspended in Tris buffer. The results of the investigation are statistically evaluated and discussed.

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