Elsevier

Mechanisms of Development

Volume 109, Issue 2, December 2001, Pages 433-436
Mechanisms of Development

Gene expression pattern
Tissue-specific expression of the Ets gene Xsap-1 during Xenopus laevis development

https://doi.org/10.1016/S0925-4773(01)00555-XGet rights and content
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Abstract

We report the cloning of Xenopus laevis Xsap-1 cDNA, encoding a member of the ternary complex factor subfamily of ETS transcription factors. The expression pattern of Xsap-1 was examined during Xenopus embryogenesis using whole-mount in situ hybridization. Spatial expression of Xsap-1 mRNA is first detected at the animal pole at the mid-blastula stage. During neurulation Xsap-1 is expressed in cells participating in neural tube formation, in the sensorial layer of the epidermal ectoderm, and in an anterior region of the ventral mesoderm. Later, Xsap-1 expression is observed in the eye, ear vesicle, branchial arches, heart, pronephros, in the somites, and the developing nervous system, such as fore-, mid-, and hindbrain as well as in the cranial ganglion X.

Keywords

Ets
Xsap-1
Xenopus laevis
Ternary complex factor
Serum response factor
MAP kinase

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