Interaction of kendomycin and semi-synthetic analogues with the anti-apoptotic protein Bcl-xl
Graphical abstract
Discovery of a stable and soluble Bcl-xl inhibitor derived from kendomycin has been disclosed.
Section snippets
Acknowledgments
The authors acknowledge the contributions of Drs. Yoganathan and Mark Butler for the original isolation of kendomycin.
References and notes (18)
Leukemia
(2007)- Funahashi, Y. et al. Japanese Patent 08,231,551, 1996; Chem. Abstr. 1997, 126,...
Nat. Med.
(1997)et al.Science
(1998)Cancer Res.
(2000)Biochim. Biophys. Acta
(2004)Nature
(2005)Cancer Res.
(2007)- et al.
J. Chem. Inf. Comput. Sci.
(2002) Nat. Prod. Rep.
(2005)
There are more references available in the full text version of this article.
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