Molecular Cell
Volume 43, Issue 2, 22 July 2011, Pages 263-274
ArticleThe Initiation Factor TFE and the Elongation Factor Spt4/5 Compete for the RNAP Clamp during Transcription Initiation and Elongation
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Graphical Abstract
Highlights
► The RNAP clamp coiled coil and RNAP stalk are required for TFE binding and activity ► The elongation factor Spt4/5 can inhibit PIC formation and transcription initiation ► TFE efficiently prevents inhibition of transcription initiation by Spt4/5 ► Spt4/5 displaces TFE from the TEC
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Present address: Institute for Physical and Theoretical Chemistry, Braunschweig University of Technology, 38106 Braunschweig, Germany
Copyright © 2011 Elsevier Inc.