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Chromosomal segments underlying quantitative trait loci for mohair production in Angora goats

Published online by Cambridge University Press:  20 November 2009

E.M. Cano ,
S. Debenedetti ,
M. Abad ,
D. Allain ,
H.R. Taddeo  and
M.A. Poli
E.M. Cano*
Affiliation:
INTA, Instituto de Genética ‘Ewald A. Favret’, CICVyA, cc 25, B1712WAA-Castelar-Buenos Aires, Argentina
S. Debenedetti
Affiliation:
INTA, Estación Experimental Agropecuaria Bariloche, cc 277, S.C. Bariloche, 8400, Río Negro, Argentina
M. Abad
Affiliation:
INTA, Estación Experimental Agropecuaria Bariloche, cc 277, S.C. Bariloche, 8400, Río Negro, Argentina
D. Allain
Affiliation:
INRA, Station d'Amélioration Génétique des Animaux, BP27, 31326 Castanet Tolosan, France
H.R. Taddeo
Affiliation:
INTA, Estación Experimental Agropecuaria Bariloche, cc 277, S.C. Bariloche, 8400, Río Negro, Argentina
M.A. Poli
Affiliation:
INTA, Instituto de Genética ‘Ewald A. Favret’, CICVyA, cc 25, B1712WAA-Castelar-Buenos Aires, Argentina
*
Correspondence to: E.M. Cano, INTA, Instituto de Genética ‘Ewald A. Favret’, CICVyA, cc 25, B1712WAA-Castelar-Buenos Aires, Argentina. email: mcano@cnia.inta.gov.ar
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Summary

This study reports the results obtained in the search of chromosomal regions affecting fleece traits in a population of Angora goats in the Argentinean Patagonia. Six hundred thirty-four offspring from 14 parental half-sib families were used. Nine phenotypic fleece traits were recorded at 4 and 11 months of age. A genome examination using 85 informative molecular markers was conducted. A linkage analysis was performed using a regression interval analysis. Our study identified 10 genomic regions affecting the average fibre diameter, coefficient of variation of the average fibre diameter, percentage of fibres with diameters over 30 µm, greasy fleece weight, staple length, average curvature of fibres, percentage of continuous medullated fibres and percentage of kemp fibres located on five goat chromosomes (1, 2, 5, 13 and 19). These results show that the average size of the quantitative trait loci effect was 1.6 phenotypic standard deviations for different traits and families. The aims of quantitative trait loci detection is the potential use of these molecular markers to increase accuracy in predicting the genetic merit of breeding and its implementation in animal breeding schemes through marker-assisted selection.

Résumé

Dans cette étude, on signale les résultats obtenus dans la recherche des régions chromosomiques relatives aux caractéristiques de la toison des chèvres angora dans la Patagonie argentine. On a utilisé 634 descendants de 14 familles à descendance uniparentale et enregistré neuf caractères phénotypiques de la toison à 4 et 11 mois. Un examen du génome a été entrepris en utilisant 85 marqueurs moléculaires informatifs. L'analyse du groupe de liaison a été effectuée en utilisant une analyse de l'intervalle de régression. Notre étude a identifié 10 régions génomiques qui affectent le diamètre moyen de la fibre, le coefficient de variation du diamètre moyen de la fibre, le pourcentage de fibre ayant un diamètre supérieur à 30 µm, le poids de la laine en suint, la longueur de la fibre, la courbure moyenne de la fibre, le pourcentage de fibres médullaires continues et le pourcentage de fibre de jarre située sur cinq chromosomes de chèvre (1, 2, 5, 13 et 19). Ces résultats indiquent que la taille moyenne de l'effet QTL était des déviations phénotypiques standard de 1,6 pour les différents caractères et familles. Le but de la détection des QTL est l'utilisation potentielle de ces marqueurs moléculaires en vue d'accroître la précision dans la prévision de la valeur génétique de la sélection et sa mise en œuvre dans les programmes de sélection animale par le biais de la sélection assistée par marqueurs.

Resumen

En este estudio, informamos sobre los resultados obtenidos en la búsqueda de regiones cromosómicas que afectan a las características del vellón en una población de cabras de Angora en la Patagonia Argentina. Se utilizaron seiscientos treinta y cuatro crías de 14 familias parentales de medios hermanos. A la edad de 4 meses y de 11 meses, se registraron nueve rasgos fenotípicos en relación al vellón. Se realizó una inspección del genoma utilizando 85 marcadores moleculares informativos. Se llevó a cabo un análisis de ligamiento utilizando un análisis de regresión de intervalo. Nuestro estudio identificó diez regiones genómicas que afectaban al diámetro promedio de fibra, coeficiente de variación de diámetro promedio de fibra, porcentaje de fibra con diámetro superior a 30 µm, peso de lana suarda, longitud de la fibra, valor promedio de la curvatura de la fibra, porcentaje de fibras meduladas continuas y porcentaje de fibras kemp localizadas en cinco cromosomas caprinos (1, 2, 5, 13 y 19). Estos resultados indican que el tamaño promedio del efecto QTL era de 1.6 desviaciones estándar fenotípicas para diferentes rasgos y familias. La detección de QTL tiene como propósito el uso potencial de estos marcadores moleculares para aumentar la precisión a la hora de pronosticar el mérito genético en la crianza, y su utilización en proyectos de crianza de animales a través de la selección asistida por marcadores.

Keywords

Angora goatsmohairquantitative trait locichèvres Angoramohairloci à effets quantitatifsAngoramohairloci de rasgos cuantitativos
Type
Research Article
Information
Animal Genetic Resources/Resources génétiques animales/Recursos genéticos animales , Volume 45 , October 2009 , pp. 107 - 112
Copyright
Copyright © Food and Agriculture Organization of the United Nations 2009

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