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Spinal Cord and Intradural-Extraparenchymal Spinal Tumors: Current Best Care Practices and Strategies

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Abstract

The management of patients with intradural spinal tumors differs in many respects from approaches taken for patients with intracranial tumors. Intramedullary lesions are often completely surrounded by normal spinal cord, displacing vital functional tracts eccentrically. Extramedullary lesions can drastically compress the spinal cord and nerve roots, reducing normal tissue to a ribbon-like consistency. The small amount of normal tissue relative to tumor has implications for surgery and postoperative adjuvant therapy. In addition, operative intervention must take spinal stability into consideration. In this report, we describe the current best care practices and strategies for patients with a diagnosis of spinal astrocytoma, ependymoma, hemangioblastoma, schwannoma, and meningioma. Treatment of patients with intradural tumors of the spinal cord and adjoining structures has changed over the past 20 years. Advances in many disciplines including neuroradiology, neurosurgery, neurooncology, and neuropathology have contributed to expediting diagnosis and improving outcomes.

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Authors and Affiliations

  1. University of California, 505 Parnassus Avenue, M-779, USA

    Andrew T. Parsa

  2. UCSF-Department of Neurological Surgery, San Francisco, California, 94143, USA

    Andrew T. Parsa

  3. Department of Neurological Surgery, University of California, USA

    Janet Lee, Ian F. Parney, Philip Weinstein & Christopher Ames

  4. Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, San Francisco, CA, USA

    Paul C. McCormick

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Parsa, A.T., Lee, J., Parney, I.F. et al. Spinal Cord and Intradural-Extraparenchymal Spinal Tumors: Current Best Care Practices and Strategies. J Neurooncol 69, 291–318 (2004). https://doi.org/10.1023/B:NEON.0000041889.71136.62

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