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Intercellular Communication and the Control of Tissue Growth: Lack of Communication between Cancer Cells

Abstract

EVIDENCE for direct cell-to-cell communication is now available for a wide variety of epithelial tissues1–4. At the surfaces of cell contact (junctional surfaces), the cell membranes in these tissues are normally so permeable that many cellular ions and molecules may diffuse rather freely from one cell interior to the next. This report deals with the question of whether cellular communication of this kind is involved in the control of tissue growth.

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LOEWENSTEIN, W., KANNO, Y. Intercellular Communication and the Control of Tissue Growth: Lack of Communication between Cancer Cells. Nature 209, 1248–1249 (1966). https://doi.org/10.1038/2091248a0

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