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Rous Sarcoma Virus: a Function required for the Maintenance of the Transformed State

Abstract

A temperature sensitive RNA tumour virus mutant has been isolated whose properties indicate that part of the viral genome is required for transformation but not for growth.

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References

  1. Dulbecco, R., Science, 166, 962 (1969).

    Article  ADS  CAS  Google Scholar 

  2. Eckhart, W., Nature, 224, 1069 (1969).

    Article  ADS  CAS  Google Scholar 

  3. Rubin, H., Virology, 1, 445 (1955).

    Article  CAS  Google Scholar 

  4. Temin, H. M., and Rubin, H., Virology, 8, 209 (1959).

    Article  CAS  Google Scholar 

  5. Vogt, P. K., Proc. US Nat. Acad. Sci., 58, 801 (1967).

    Article  ADS  CAS  Google Scholar 

  6. Zavada, J., and Macpherson, I., Nature, 225, 24 (1970).

    Article  ADS  CAS  Google Scholar 

  7. Hanafusa, H., and Hanafusa, T., Virology, 34, 630 (1968).

    Article  CAS  Google Scholar 

  8. Valentine, A. F., and Bader, J. P., J. Virol., 2, 224 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Chang, S. S., Toni, R. J., Gilden, R. V., Hatanaka, M., and Huebner, R. J., J. Gen. Virol., 5, 443 (1969).

    Article  Google Scholar 

  10. Svoboda, J., Machala, O., and Hlozanek, I., Folia Biol., 13, 155 (1967).

    Google Scholar 

  11. Fried, M., Virology, 25, 669 (1965).

    Article  CAS  Google Scholar 

  12. Eckhart, W., Virology, 38, 120 (1969).

    Article  CAS  Google Scholar 

  13. Di Mayorca, G., Callender, J., Marin, G., Giordano, R., Virology, 38, 126 (1969).

    Article  CAS  Google Scholar 

  14. Fried, M., Proc. US Nat. Acad. Sci., 53, 486 (1965).

    Article  ADS  CAS  Google Scholar 

  15. Stoker, M., and Dulbecco, R., Nature, 223, 397 (1969).

    Article  ADS  CAS  Google Scholar 

  16. Duesberg, P. H., Current Topics in Microbiology and Immunology, 51, 79 (1970).

    Book  Google Scholar 

  17. Goldé, A., Virology (in the press).

  18. Rubin, H., Proc. US Nat. Acad. Sci., 46, 1105 (1960).

    Article  ADS  CAS  Google Scholar 

  19. Vogt, P. K., and Ishizaki, R., Virology, 26, 664 (1965).

    Article  CAS  Google Scholar 

  20. Rubin, H., Exp. Cell Res., 41, 149 (1966).

    Article  CAS  Google Scholar 

  21. Bader, J. P., J. Cell. Physiol., 70, 301 (1967).

    Article  CAS  Google Scholar 

  22. Vogt, P. K., and Ishizaki, R., Virology, 30, 368 (1966).

    Article  CAS  Google Scholar 

  23. Ishizaki, R., and Vogt, P. K., Virology, 30, 375 (1966).

    Article  CAS  Google Scholar 

  24. Hanafusa, H., Nat. Cancer Inst. Monog., 17, 543 (1964).

    Google Scholar 

  25. Dougherty, R. M., and Rasmussen, R., Nat. Cancer Inst. Monog., 17, 337 (1964).

    Google Scholar 

  26. Goldé, A., CR Acad. Sci., 262, 329 (1966).

    Google Scholar 

  27. Graf, T., and Bauer, H., Proc. Second Intern. Cong. Oncogenic Viruses, Royaumont, 1969 (in the press).

  28. Hanafusa, H., Current Topics Microbiol. Immunol., 51, 114 (1970).

    CAS  Google Scholar 

  29. Steck, F. T., and Rubin, H., Virology, 29, 642 (1965).

    Article  Google Scholar 

  30. Macpherson, I., Science, 148, 1731 (1965).

    Article  ADS  CAS  Google Scholar 

  31. Duff, R. G., and Vogt, P. K., Virology, 39, 18 (1969).

    Article  CAS  Google Scholar 

  32. Toyoshima, K., and Vogt, P. K., Virology, 39, 930 (1969).

    Article  CAS  Google Scholar 

Download references

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MARTIN, G. Rous Sarcoma Virus: a Function required for the Maintenance of the Transformed State. Nature 227, 1021–1023 (1970). https://doi.org/10.1038/2271021a0

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