Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Review Article
  • Published:

The ribosome returns

Abstract

Fashions come and go in biochemistry. The discovery that some RNAs are enzymes is reviving interest in the long-neglected ribosome.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Cold Spring Harbor Symp. quant. Biol. 34, (1969).

  2. Wittmann, H. G. A. Rev. Biochem. 51, 155–183 (1982).

    Article  CAS  Google Scholar 

  3. Nierhaus, K. H. & Dohme, F. Proc. natn. Acad. Sci. U.S.A. 71, 4713–4717 (1974).

    Article  ADS  CAS  Google Scholar 

  4. Kurland, C. G. & Ehrenberg, M. Progr. Nucleic Acids Res. molec. Biol. 31, 191–219 (1984).

    Article  CAS  Google Scholar 

  5. Lake, J. A. A. Rev. Biochem. 54, 507–530 (1985).

    Article  CAS  Google Scholar 

  6. Stoeffler, G. & Stoeffler-Meilicke, M. A. Rev. Biophys. Bioengng 13, 303–330 (1984).

    Article  CAS  Google Scholar 

  7. Moore, P. B., Capel, M., Kjeldgaard, M. & Engelman, D. M. in Structure, Function and Genetics of Ribosomes (eds Hardesty, B. & Kramer, G.) 87–100 (Springer, New York, 1986).

    Book  Google Scholar 

  8. Kruger, K. et al. Cell 31, 145–157 (1982).

    Article  Google Scholar 

  9. Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N. & Altman, S. Cell 35, 849–857 (1983).

    Article  CAS  Google Scholar 

  10. Woese, C. R. in Ribosomes. Structure, Function and Genetics (eds Chambliss, G. et al.) 357–376 (University Park Press, Baltimore, 1980).

    Google Scholar 

  11. Moore, P. B. Proc. Robert A. Welch Conf. chem. Res. XXIX (Robert A. Welch Foundation, Houston, Texas, 1986).

    Google Scholar 

  12. Steitz, J. A. in Ribosomes. Structure, Function and Genetics (eds Chambliss, G. et al.) 479–496 (University Park Press, Baltimore, 1980).

    Google Scholar 

  13. Noller, H. F. & Woese, C. R. Science 212, 403–411 (1981).

    Article  ADS  CAS  Google Scholar 

  14. Gutell, R. R., Weiser, B., Woese, C. R. & Noller, H. F. Prog. Nucleic Acids Res. molec Biol. 32, 155–216 (1985).

    Article  CAS  Google Scholar 

  15. Brimacombe, R., Atmadja, H. J., Kyriatsoulis, A. & Stiege, W. in Structure, Function and Genetics of Ribosomes (eds Hardesty, B. & Kramer, G.) 184–202 (Springer, New York, 1986).

    Book  Google Scholar 

  16. Stern, S., Wilson, R. C. & Noller, H. F. J. molec. Biol. 192, 101–110 (1986).

    Article  CAS  Google Scholar 

  17. Capel, M. S. et al. Science 238, 1403–1406 (1987).

    Article  ADS  CAS  Google Scholar 

  18. Moore, P. B., Capel, M. S., Kjeldgaard, M. & Engelman, D. M. Abstr. 52nd Cold Spring Harbor Symp. quant. Biol. p. 23 (1987).

  19. Traut, R. R. et al. in Structure, Function and Genetics of Ribosomes (eds Hardesty, B. & Kramer, G.) 286–308 (Springer, New York, 1986).

    Book  Google Scholar 

  20. Stoeffler, G. & Stoeffler-Meilicke, M. in Structure, Function and Genetics of Ribosomes (eds Hardesty, B. & Kramer, G.) 28–46 (Springer, New York, 1986).

    Book  Google Scholar 

  21. Nowotny, V., May, R. P. & Nierhaus, K. H. in Structure, Function and Genetics of Ribosomes (eds Hardesty, B. & Kramer, G.) 101–111 (Springer, New York, 1986).

    Book  Google Scholar 

  22. Expert-Bezancon, A. & Wollenzien, P. J. molec. Biol. 184, 53–66 (1985).

    Article  CAS  Google Scholar 

  23. Noller, H. F. et al. Abstr. 52nd Cold Spring Harbor Symp. quant. Biol. p. 21 (1987).

  24. Moazed, D. & Noller, H. F. Cell 47, 985–994 (1986).

    Article  CAS  Google Scholar 

  25. Barta, A., Steiner, G., Brosius, J., Noller, H. F. & Kuechler, E. Proc. natn. Acad. Sci. U.S.A. 81, 3607–3611 (1984).

    Article  ADS  CAS  Google Scholar 

  26. Gavrilova, L. P., Kostiashkina, O. E., Koteliansky, V. E., Rutkevitch, N. M. & Spirin, A. S. J. molec. Biol. 101, 537–522 (1976).

    Article  CAS  Google Scholar 

  27. Jacob, W. F., Santer, M. & Dahlberg, A. E. Proc. natn. Acad. Sci. U.S.A 84, 4757–4761 (1987).

    Article  ADS  CAS  Google Scholar 

  28. Hui, A. & de Boer, H. A. Proc. natn. Acad. Sci. U.S.A. 84, 4762–4766 (1987)

    Article  ADS  CAS  Google Scholar 

  29. Krzyzosiak, W. et al. Biochemistry 26, 2353–2364 (1987).

    Article  CAS  Google Scholar 

  30. Yonath, A., Leonard, K. R. & Wittmann, H. G. Science 236, 813–816 (1987).

    Article  ADS  CAS  Google Scholar 

  31. Yonath, A. et al. Abstr. 52nd Cold Spring Harbor Symp. quant. Biol. 24–25 (1987).

  32. Engelman, D. M. & Moore, P. B. Scient. Am. 235, 44–57 (1976).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Moore, P. The ribosome returns. Nature 331, 223–227 (1988). https://doi.org/10.1038/331223a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/331223a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing