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The protein encoded by the Arabidopsis homeotic gene agamous resembles transcription factors

Abstract

Mutations in the homeotic gene agamous of the plant Arabidopsis cause the transformation of the floral sex organs. Cloning and sequence analysis of agamous suggest that it encodes a protein with a high degree of sequence similarity to the DNA-binding region of transcription factors from yeast and humans and to the product of a homeotic gene from Antirrhinum. The agamous gene therefore probably encodes a transcription factor that regulates genes determining stamen and carpel development in wild-type flowers.

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References

  1. Meyerowitz, E. M. Rev. Genet. 21, 93–111 (1987).

    Article  CAS  Google Scholar 

  2. Meyerowitz, E. M. Cell 56, 263–269 (1989).

    Article  CAS  Google Scholar 

  3. Bowman, J. L., Smyth, D. R. & Meyerowitz, E. M. The Plant Cell 1, 37–52 (1989).

    Article  CAS  Google Scholar 

  4. Koornneef, M. in Genetic Maps 1987 742–745 (Cold Spring Harbor Laboratory, New York, 1987).

    Google Scholar 

  5. Pruitt, R. E., Chang, C., Pang, P. P. & Meyerowitz, E. M. in 45th Symposium of the Society for Developmental Biology (ed. Loomis, W.) 327–338 (Liss, New York, 1987).

    Google Scholar 

  6. Komaki, M. K., Okada, K., Nishino, E. & Shimura, Y. Development 104, 195–203 (1988).

    Google Scholar 

  7. Kunst, L., Klenz, J. E., Martinez-Zapater, J. & Haughn, G. W. The Plant Cell 1, 1131–1135 (1989).

    Article  Google Scholar 

  8. Meyerowitz, E. M., Smyth, D. R. & Bowman, J. L. Development 106, 209–217 (1989).

    Google Scholar 

  9. Braun, A. Gesell. Naturforsch. Freunde z. Berlin p. 75 (1873).

  10. Conrad, D. Biol. Zentralbl. 90, 137–144 (1971).

    Google Scholar 

  11. Koornneef, M., de Bruine, J. H. & Goettsch, P. Arabidopsis Inf. Serv. 17, 11–18 (1980).

    Google Scholar 

  12. Feldmann, K. A., Marks, M. D., Christianson, M. L. & Quatrano, R. S. Science 243, 1351–1354 (1989).

    Article  ADS  CAS  Google Scholar 

  13. Feldmann, K. A. & Marks, M. D. Molec. Gen. Genet. 208, 1–9 (1987).

    Article  CAS  Google Scholar 

  14. Chang, C., Bowman, J. L., DeJohn, A. W., Lander, E. S. & Meyerowitz, E. M. Proc. natn. Acad. Sci. U.S.A. 85, 6856–6860 (1988).

    Article  ADS  CAS  Google Scholar 

  15. Lipman, D. J. & Pearson, W. R. Science 227, 1435–1441 (1985).

    Article  ADS  CAS  Google Scholar 

  16. Norman, C., Runswick, M., Pollock, R. & Triesman, R. Cell 55, 989–1003 (1988).

    Article  CAS  Google Scholar 

  17. Passmore, S., Maine, G. T., Elble, R., Christ, C. & Tye, B. K. J. molec. Biol 204, 593–606 (1988).

    Article  CAS  Google Scholar 

  18. Dubois, E., Bercy, J. & Messenguy, F. Molec. Gen. Genet. 207, 142–148 (1987).

    Article  CAS  Google Scholar 

  19. Sommer, H. et al. EMBO J. 9, 605–613 (1990).

    Article  CAS  Google Scholar 

  20. Smyth, D. R., Bowman, J. L. & Meyerowitz, E. M. Plant Cell 2 (in the press).

  21. Herskowitz, I. Nature 342, 749–757 (1990).

    Article  ADS  Google Scholar 

  22. Hayes, T. E., Kitchen, A. M. & Cochran, B. H. Proc. natn. Acad. Sci. U.S.A. 84, 1272–1276 (1987).

    Article  ADS  CAS  Google Scholar 

  23. Murre, C. et al. Cell 58, 537–544 (1989).

    Article  CAS  Google Scholar 

  24. Ingham, P. W. Nature 335, 25–34 (1988).

    Article  ADS  CAS  Google Scholar 

  25. Schröter, H., Mueller, C. G. F., Meese, K. & Nordheim, A. EMBO J. 9, 1123–1130 (1990).

    Article  Google Scholar 

  26. Fraley, R. T. et al. Bio/ Technology 3, 629–635 (1985).

    CAS  Google Scholar 

  27. Lloyd, A. M. et al. Science 234, 464–466 (1986).

    Article  ADS  CAS  Google Scholar 

  28. Velten, J. & Schell, J. Nucleic Acids Res. 13, 6981–6998 (1985).

    Article  CAS  Google Scholar 

  29. Crawford, N. M., Campbell, W. H. & Davis, R. W. Proc. natn. Acad. Sci. U.S.A. 83, 8073–8076 (1986).

    Article  ADS  CAS  Google Scholar 

  30. Ma, H., Yanofsky, M. F. & Meyerowitz, E. M. Proc. natn. Acad. Sci. U.S.A. 87, 3821–3825 (1990).

    Article  ADS  CAS  Google Scholar 

  31. Barker, S. J., Harada, J. J. & Goldberg, R. B. Proc. natn. Acad. Sci. U.S.A. 85, 458–462 (1988).

    Article  ADS  CAS  Google Scholar 

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Yanofsky, M., Ma, H., Bowman, J. et al. The protein encoded by the Arabidopsis homeotic gene agamous resembles transcription factors. Nature 346, 35–39 (1990). https://doi.org/10.1038/346035a0

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