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Gene regulation

Code of silence

Using genetic approaches and a filamentous fungus, molecular biologists have found further evidence of an intimate relationship between genomes and the histone proteins that evolved to package them.

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Figure 1: Methylation-associated models of gene silencing.

References

  1. Tamaru, H. & Selker, E. U. Nature 414, 277–283 (2001).

    Article  ADS  CAS  Google Scholar 

  2. Rice, J. C. & Allis, C. D. Curr. Opin. Cell Biol. 13, 263–273 (2001).

    Article  CAS  Google Scholar 

  3. Ng, H. H. & Bird, A. Curr. Opin. Genet. Dev. 9, 158–163 (1999).

    Article  CAS  Google Scholar 

  4. Jenuwein, T., Laible, G., Dorn, R. & Reuter, G. Cell. Mol. Life Sci. 54, 80–93 (1998).

    Article  CAS  Google Scholar 

  5. Rea, S. et al. Nature 406, 593–599 (2000).

    Article  ADS  CAS  Google Scholar 

  6. Nakayama, J., Rice, J. C., Strahl, B. D., Allis, C. D. & Grewal, S. I. Science 292, 110–113 (2001).

    Article  ADS  CAS  Google Scholar 

  7. Mann, R. K. & Grunstein, M. EMBO J. 11, 3297–3306 (1992).

    Article  CAS  Google Scholar 

  8. Jenuwein, T. & Allis, C. D. Science 293, 1074–1080 (2001).

    Article  CAS  Google Scholar 

  9. Bannister, A. J. et al. Nature 410, 120–124 (2001).

    Article  ADS  CAS  Google Scholar 

  10. Lachner, M., O'Carroll, D., Rea, S., Mechtler, K. & Jenuwein, T. Nature 410, 116–120 (2001).

    Article  ADS  CAS  Google Scholar 

  11. Eissenberg, J. C. & Elgin, S. C. Curr. Opin. Genet. Dev. 10, 204–210 (2000).

    Article  CAS  Google Scholar 

  12. Nielsen, S. J. et al. Nature 412, 561–565 (2001).

    Article  ADS  CAS  Google Scholar 

Download references

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Correspondence to C. David Allis.

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Rice, J., Allis, C. Code of silence. Nature 414, 259–261 (2001). https://doi.org/10.1038/35104721

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