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Brain evolution (Communication arising)

Analysis of mammalian brain architecture

Abstract

The mammalian brain is composed of several distinct parts which show different growth in evolution. Clark, Mitra and Wang1 found that the two main cortices of the brain — the cerebral (neo-) cortex and the cerebellum — show very different growth, and that whereas the ratio of neocortex volume to total brain volume increases with evolution, the cerebellum occupies a constant proportion in different species. Here I compare the surface areas of the two cortices in different species and find that these show a simple proportionality. Contrary to the conclusion drawn by Clark et al.1, this linear dependence of size implies that the two major cortices increase their computational capacity in parallel, suggesting a functional dependence of the one upon the other.

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Figure 1: Logarithmic plot of cerebellar11versus cerebral cortex area12.

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References

  1. Clark, D. A., Mitra, P. P. & Wang, S. S. Nature 411, 189–193 (2001).

    Article  ADS  CAS  Google Scholar 

  2. Matano, S., Stephan, H. & Baron, G. Folia Primatol. 44, 171–181 (1985).

    Article  CAS  Google Scholar 

  3. Hofman, M. A. Brain Behav. Evol. 27, 28–40 (1985).

    Article  CAS  Google Scholar 

  4. Frahm, H. D., Stephan, H. & Stephan, M. J. Hirnforsch. 23, 375–389 (1982).

    CAS  PubMed  Google Scholar 

  5. Korbo, L., Andersen, B. B., Ladefoged, O. & Moller, A. Brain Res. 609, 262–268 (1993).

    Article  CAS  Google Scholar 

  6. Andersen, B. B., Korbo, L. & Pakkenberg, B. J. Comp. Neurol. 326, 549–560 (1992).

    Article  CAS  Google Scholar 

  7. Braitenberg, V. J. Comput. Neurosci. 10, 71–77 (2001).

    Article  CAS  Google Scholar 

  8. Zhang, K. & Sejnowski, T. J. Proc. Natl Acad. Sci. USA 97, 5621–5626 (2000).

    Article  ADS  CAS  Google Scholar 

  9. Braitenberg, V. & Schüz, A. Anatomy of the Cortex (Springer, Berlin, 1991).

    Book  Google Scholar 

  10. Braitenberg, V., Heck, D. & Sultan, F. Behav.Brain Sci. 20, 229–245 (1997).

    Article  CAS  Google Scholar 

  11. Sultan, F. & Braitenberg, V. J. Hirnforsch. 34, 79–92 (1993).

    CAS  PubMed  Google Scholar 

  12. Brodmann, K. Verhandlungen der 85. Versammlung deutscher Naturforscher und Ärzte in Wien 85, 200–240 (1913).

    Google Scholar 

Download references

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Correspondence to Fahad Sultan.

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Sultan, F. Analysis of mammalian brain architecture. Nature 415, 133–134 (2002). https://doi.org/10.1038/415133b

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