Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Neurodegenerative disease

Cut to the chase

A family of enzymes called caspases — best known for their involvement in programmed cell death — now seems to be pivotal in the progression of two neurodegenerative diseases.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Galvan, V. et al. Proc. Natl Acad. Sci. USA 103, 7130–7135 (2006).

    Article  ADS  CAS  Google Scholar 

  2. Graham, R. K. et al. Cell 125, 1179–1191 (2006).

    Article  CAS  Google Scholar 

  3. Gervais, F. G. et al. Cell 97, 395–406 (2000).

    Article  Google Scholar 

  4. Lu, D. C. et al. Nature Med. 6, 397–404 (2000).

    Article  CAS  Google Scholar 

  5. Wellington, C. L. et al. J. Biol. Chem. 275, 19831–19838 (2000).

    Article  CAS  Google Scholar 

  6. Hermel, E. et al. Cell Death Differ. 11, 424–438 (2004).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ellerby, L., Orr, H. Cut to the chase. Nature 442, 641–642 (2006). https://doi.org/10.1038/442641a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/442641a

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing